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We are close to announcing our next NUTechScan campaign after the incredible success of our first one! Watch this space..........@NUBiosciences Newcastle: Innovation, Methodology & Application #singlecellanalysis #flowcytometry

In conclusion, OPTIMAL is not a new analysis pipeline per se for IMC or any other multi-plexed tissue imaging data, but it does provide a simple framework for assessing any approach. As we convert segmentation data to .FCS file format, it also makes onward analysis accessible.

We also looked at data transformation using different arcsinh cofactor values and used the Fisher Discrimination Ratio, also know as Linear Discriminate Analysis, to determine a value of 1 gave the best statistical separation between low and high parameter values.

OPTIMAL: An OPTimsed Imaging Mass cytometry AnaLysis framework for Segmentation and Data Exploration biorxiv.org/content/10.110… Great to see this out finally. Standard BioTools #ImagingMassCytometry #singlecellanalysis

After the first very successful NUTechScan campagin to evaluate and now secure the miltenyibiotec MACSima system....what is next on the horizon! Watch this space.......

First grant success for NUTechScan ! Awarded ~£1 million from the Medical Research Council mid-level equipment call. Bids led by Andy Filby of Newcastle FCCF Dr Kelly Coffey and Alex Laude of Bio-Imaging Unit-Newcastle University and supported by many others Newcastle University @NUBiosciences shout out to FMSgrantfunding

Great trip to San Jose to attend the Deepcell scientific summit. Heading back to Newcastle University and Newcastle: Innovation, Methodology & Application and NUTechScan with a head full of ideas about how we can use their cool tech to address novel questions and revist old #flowcytometry #morphometrics

One is a marvel of German engineering and design...the other is a BMW ;-) Our first NUTechScan campaign is about to begin with miltenyibiotec #spatial #singlecellanalysis non #flowcytometry ;-) Newcastle FCCF Bio-Imaging Unit-Newcastle University

Super second NUTechScan Newcastle: Innovation, Methodology & Application seminar this morning from Akoya Biosciences all about their PhenoCycler Fusion system.

Great first Newcastle: Innovation, Methodology & Application NUTechScan seminar yesterday from NanoString discussing their spatial analysis platforms, including the new COSMX #multiomics system. Such an exciting time to be involved in #horizonscanning for new technologies in the biomedical space!

Not one, but TWO exciting roles with the world-leading Bio-Imaging Unit-Newcastle University First role is for a dedicated #bioimaging #datanalyst tinyurl.com/2p9h57df and second one to support the wonderful work of the QUAREP-LiMi global initiative tinyurl.com/5n6bn7cy #singlecellanalysis

Great interview piece with the Newcastle FCCF director and Newcastle: Innovation, Methodology & Application @NUBiosciences theme lead, Dr Andrew Filby from Newcastle University who won the Times Higher Education technician of the year 2021 #iamatechnician #TechniciansMakeItHappen

tinyurl.com/mpsuntzx