Woolly Mammoth Skin "Freeze-Dried" For 52,000 Years Delivers First-Ever 3D Chromosomes iflscience.com/woolly-mammoth…

On the frozen tundra of Siberia some 50,000 years ago, a woolly mammoth met its end under mysterious circumstances go.nature.com/4cDmu2Q

I'm dead after reading this spectacular publication. It has everything: brilliant science, fancy techniques, a shooting, baseball, extinct animals, donkeys, cars.

For the first time, researchers have reconstructed the 3D structure of ancient genetic material, in this case from a 52,000-year-old mammoth trib.al/URmoamo

Thanks to Ragini Mahajan and Mahdi Sadr for video production!

Fossil chromosomes have been found preserved in a 52,000-year-old mammoth 🦣🧬 But the way they're preserved could revolutionise our understanding of ancient life Listen to me on The Economist pod 🧵 shows.acast.com/theintelligenc…

Thank you to Ragini Mahajan and Mahdi Sadr for video production!

First ever 3D reconstruction of woolly #mammoth chromosomes thanks to serendipitously freeze-dried skin. Read more in Cell: cell.com/cell/fulltext/… Erez Lieberman Aiden Olga Dudchenko 🇺🇦 Marc A. Marti-Renom

Woolly mammoth genome reconstructed in 3D from fossil chromosomes lemonde.fr/en/science/art…

I hope folks will check this out! We had a lot of fun with this. Thank you to Ragini Mahajan and Mahdi Sadr for video production, Adam Fotos for cover image, also Suno & OpenAI ChatGPT !

On the frozen tundra of Siberia some 50,000 years ago, a woolly mammoth met its end under mysterious circumstances go.nature.com/4bFhXf2

A new paper describes the discovery of fossil chromosomes—coiled-up strands of DNA millions of base pairs long—inside the cells of mammoths that died tens of thousands of years ago econ.st/3zzLqtz 👇

An amazing team effort. Glad we are finally able to share all the details!

First ever 3D reconstruction of woolly #mammoth chromosomes thanks to serendipitously freeze-dried skin. Read more in Cell: cell.com/cell/fulltext/… Erez Lieberman Aiden Olga Dudchenko 🇺🇦 Marc A. Marti-Renom

On the frozen tundra of Siberia some 50,000 years ago, a woolly mammoth met its end under mysterious circumstances go.nature.com/3WnZ0ZY

Image of the Month: The wooly #mammoth emerges from the past. blogs.bcm.edu/2024/07/17/fro… via BCMHouston Erez Lieberman Aiden Olga Dudchenko 🇺🇦 Juan A. Rodríguez Marc A. Marti-Renom University of Copenhagen Research CNAG Centre for Genomic Regulation (CRG) Cell

Woolly mammoth DNA in an exceptional state of preservation has been obtained from 52,000-year-old freeze-dried 'jerky'. It’s even possible to reconstruct the 3D structure of the chromosomes, which may help efforts to resurrect the species. newscientist.com/article/243921…

I updated our webpage for openings at our #CDlab: ceesdekkerlab.nl/come-join-us/ So feel free to apply if you are an ambitious young scientist interested in doing a postdoc (or PhD) in our biophysics lab! RT=nice!

[NEW] A veritable stampede of researchers banded together to shoulder a truly mammoth task that takes #epigenetics pre-historic! Using PaleoHi-C, they've described the 3D genome architecture of preserved cells from 52,000-year-old animal skin! 🦣bit.ly/3WwlIiJ

Excited to share our new paper Nature Communications. bit.ly/3WUkxbJ Single-nucleosome imaging reveals that condensins act as molecular crosslinkers, locally constraining nucleosomes to organize mitotic chromosomes. Nucleosome-nucleosome interactions constrain whole chromosomes.