In situ amyloid in Alzheimer's brain! These tomos still blow my mind 🤯. Grateful to work with the best team Joshua Jenkins Nayab Tom Yehuda Halfon 🏳️‍🌈 René Frank RadfordLab Jeroen Hoozemans #teamtomo and to all those who donate their brains to science ❤️ biorxiv.org/content/10.110…

Thank you to all my lovely group members and collaborators The Astbury Centre and elsewhere. I share this with all of you. And big thanks to those who nominated and supported me at the Biochemical Society

Thank you all for your kind messages sent to me following the announcement of the Centenary award of the Biochemical Society . I am truly grateful to you all, my friends!

Very proud of Katy Dewison for her award of joint first prize for her talk on synuclein aggregation at the Faculty of Biological Sciences postgraduate symposium. Great science and great talk Katy!

This is a brilliant opportunity to join a vibrant community of structural biologists in Cryo-ET. As part of our community we want you to work towards becoming a world leader in this field. The Astbury Centre Faculty of Biological Sciences please RT! jobs.leeds.ac.uk/vacancy.aspx?r…

Proud of Taya from the lab presenting her first external talk at the UK DRI ECR Parkinson's disease meeting - well done Taya! Kwok Lab

Professor Sheena Radford has been elected as an international member of the National Academy of Sciences 👏 Commenting on her award, she said she was 'humbled, honoured and delighted" and looks forward to helping deliver its aims. biologicalsciences.leeds.ac.uk/biological-sci…

Excited to share our last work in J. Am. Chem. Soc., with RadfordLab, Antoine loquet, Frank Sobott, Jan Skov Pedersen, Daniel Otzen, JM Valpuesta & A Muga   A bit closer to understand #synuclein #oligomers and their transition to #amyloids in #Parkinson A thread 🧵 (1/7)  pubs.acs.org/doi/10.1021/ja…

Interested in intrinsically disordered regions of proteins? There is an IDR meeting at the University of Leeds on the 10th of June. Please come and join us to discuss exciting IDR research! Register here: spidr-slola.com/early-career-r… Spidr Idp

Glad to have passed my PhD viva! Thank you to my examiners for such a great discussion LeneyMassSpectrometry Morgan Herod Lab! And of course to my supervisor Anton Calabrese!

Delighted to see @chalmerscccc work at the interface of nanopore sensing and cell biology published Nature Communications . Great team effort RadfordLab Eric Hewitt AksimentievLab nature.com/articles/s4146…

We had a brilliant time at our amyloid symposium this week. A fantastic team to be part of with lots of great science in the works

Fantastic opportunity to join Faculty of Biological Sciences The Astbury Centre as a Lecturer, and take advantage of significant investment in cryo-EM and cryo-ET, to build an ambitious research programme! jobs.leeds.ac.uk/vacancy.aspx?r…

Thrilled to see our in-tissue cryoET work on amyloids out in Nature! It’s been a really fun collaboration with all involved. Maddie Gilbert, Nayab Fatima, Tom O’Sullivan, René Frank, AstburyBiostructure. #TeamTomo. nature.com/articles/s4158…

Scientists have described a new approach to designing proteins from scratch. It uses Transmembrane β-barrel pores, nanosized proteins which are used in analysis methods that can help detect disease. biologicalsciences.leeds.ac.uk/biological-sci…

So proud to be part of this great collaboration with Anastassia Vorobieva and David Baker. Well done to James Whitehouse who did all the membrane protein folding work!

Excited to share our latest findings on the amino acids involved in regulating alpha-synuclein amyloid formation. Out now in PNAS! Congratulations to all involved! pnas.org/doi/10.1073/pn…

Having a great time at #imsc2024… A fantastic programme with lots of amazing #massspec research on display. Both Adam and Emily Byrd from our group were able to share some of our latest science too!

New paper from our team using smFRET MS and cryoEM to see SurA delivering OMPs to BAM. Well done all - proud to work with you all! rdcu.be/dSDfs.

Amazing efforts from the first author Francesca Chandler showed the mode of action by #cryoEM where 2 small molecules glue a 16-subunit protein complex. Animation credit Jeroen Claus Phospho