Delighted to have our paper accepted for publication RPTH! Thank you to all co-authors for their help, in particular Robert Campbell and Abigail Ajanel for supporting me during my ISTH training fellowship last year!

Low albumin + high genetic risk = significantly increased VTE risk. This study from the UK Biobank suggests a joint effect of ALB levels and genetics on VTE incidence. 🧐Full details: rpthjournal.org/article/S2475-… #Thrombosis

Do you find it difficult to determine anticoagulant status from electronic health records? 💻 This #RPTHJournal Brief Report from Mansour Gergi MD developed an algorithm with 95% sensitivity and 98% accuracy to acquire that information. Check it out here: rpthjournal.org/article/S2475-…

🩸🦴Integrating musculoskeletal ultrasound into #hemophilia care revolutionizes joint health! A 3-year study from Azusa Nagao, MD, MSc, PhD and colleagues shows early detection & personalized prophylaxis adjustments significantly improve outcomes in patients with hemophilia A/B. Read more

We love to see it!

Venous thromboembolism in cancer significantly impacts quality of life, yet few tools measure this effect. This #RPTHJournal review shows that more research is needed to enhance care and improve outcomes for cancer patients with VTE. 🩸🔬 rpthjournal.org/article/S2475-…

Unemployment due to disability is higher in adults with hemophilia. The ADVANCE study shows prophylactic treatment reduces this risk, emphasizing the importance of proactive care. 💉💼 rpthjournal.org/article/S2475-…

The RISAPS trial is investigating whether high-dose rivaroxaban could be a safe and effective alternative to high-intensity warfarin for secondary prevention in APS patients with ischemic stroke. Results could pave the way for new treatment options. 🧠💉 rpthjournal.org/article/S2475-…

Q: Does Rivaroxaban reduce the rate of recurrent VTE in patients with a history of DVT? A: @yoshitoogihara and the ICE CALF DVT team found that Rivaroxaban reduced rates of recurrence with a small risk of bleeding. Check out the data here: rpthjournal.org/article/S2475-…

Predicting #sepsis -induced DIC before it becomes overt is crucial. 🤖A new #MachineLearning model outperforms conventional methods, offering better accuracy in early detection. Could this be a game-changer for sepsis care? rpthjournal.org/article/S2475-…

New Case Report in #RPTHJournal! Acquired von Willebrand syndrome can mimic type 2B VWD, as seen in a case with thrombocytopenia and bleeding symptoms. Monoclonal IgG causes VWF changes, increasing platelet binding. 🩸 rpthjournal.org/article/S2475-…

New study reveals that the loss of high-molecular-weight VWF multimers, due to excessive cleavage by ADAMTS13, occurs just before the onset of transplant-associated thrombotic microangiopathy (TA-TMA). 🩸 More insight here: rpthjournal.org/article/S2475-…

The association of antiplatelet agents with mortality among patients with non–COVID-19 community-acquired pneumonia: a systematic review and meta-analysis - Research and Practice in Thrombosis and Haemostasis rpthjournal.org/article/S2475-…

Did you know that patients with Chronic Kidney Disease have an increased risk of spontaneous major bleeds?🩸 Bleeding risk was highest in CKD patients with 🔴low endogenous thrombin potential 🔴low hemostatic potential 🔴low PAI-1 Read here: rpthjournal.org/article/S2475-…

Cool new science couples flow cytometry with machine learning to identify activated platelet subtypes! Ami Vadgama Nicola Dark Harriet Allan Paul Armstrong Tim Warner Elsevier Hematology ➡️rpthjournal.org/article/S2475-…

New #RPTHJournal Brief Report reveals that TMX1 counteracts ERp46 to maintain #platelet quiescence by oxidizing both ERp46 and integrin αIIbβ3, preventing platelet overactivation and potential #thrombosis. 👉rpthjournal.org/article/S2475-…

Detecting anti–ADAMTS-13 autoantibodies in immune-mediated thrombotic thrombocytopenic purpura (iTTP) is hard. While ADAMTS-13 activity measurements align, CLIA and ELISA differ significantly in AAb detection, especially during remission. Read here: rpthjournal.org/article/S2475-…

Check out this new podcast series from ISTH to meet early career professionals shaping the future of thrombosis and hemostasis! New episodes dropping each month.

Update on the safety of rFVIIa in #postpartumhemorrhage! Systematic review finds similar, small incidence of thromboembolic events in women treated vs. untreated with rfVIIa. Wide prediction intervals highlight the need for more robust trials. rpthjournal.org/article/S2475-…

We can't wait for this special Research Recap!