Incredibly proud of our fellow Rushin Patel MD for leading the crucial study of SGLT-2i and GLP1RA incremental benefits in HFpEF! Kudos to the dedicated mentors and fantastic team Sarju Ganatra, MD, FACC Saurabh S Dani, MD, MSc Javed Butler Gregg Fonarow MD Dr. Deepak L. Bhatt

#cardiology #cardioX JACC Journals

#SGLT2i and #GLP1 are both independently shown to benefit patients with #HFpEF #heartfailure But can #GLP1 provide incremental benefits to those already on #SGLT2i ? The answer is YES ✅️✅️✅️ For patients with #diabetes #HFpEF & #Obesity #realworlddata ➡️ Use of #GLP1

New #ESCGuidelines on #Afib 2024 The 🆕 AF-CARE pathway 💡Comorbodity and risk factor management 💡Avoid stroke 💡Reduce symptoms by rate and rhythm control 💡Evaluation and dynamic reassessment #ESCCongress European Society of Cardiology

#ESCCongress #Obesity #ESCGuidelines #CVPrev #AOM #weightloss 💊💉 Medications for weight loss: Adverse effects & Contraindications need to be discussed with patients 💊💉 How to manage side effects important 💊💉Cost effectiveness/ Willingness to Pay (WTP) threshold playing out

GLP-1 RA reduces CV events & CKD progression, independent of SGLT2i - supporting combination therapy with both agents to improve cardio-renal outcomes in type 2 diabetes Our most comprehensive analysis yet, #simpub in Circulation for #ESCCongress ahajournals.org/doi/abs/10.116…

2024 #ESCGuidelines for the management of elevated blood pressure and #hypertension: Developed by the task force on the management of elevated #BP and hypertension of European Society of Cardiology and endorsed by European Society of Endocrinology (ESE) and European Stroke Org. academic.oup.com/eurheartj/adva… #ESCCongress European Society of Cardiology Journals

Colchicine improves outcomes in coronary disease, but will it in heart failure? Discover more in #EHJ: academic.oup.com/eurheartj/adva… #ESCCongress #inflammation #colchicine #CVD #outcome European Society of Cardiology European Society of Cardiology Journals

New 2024 ESC guidelines 1-AF drive.google.com/file/d/15nQsJj… 2-Aortic and PAD drive.google.com/file/d/15ojoMm… 3-HTN drive.google.com/file/d/15jdVZu… 4-CCS drive.google.com/file/d/15pbRJR…

Multi-Institute study in JACC Journals led by Lahey Hospital investigators shows incremental benefits of #GLP1RA in addition to #SGLT2i for those with #heartfailure #HFpEF #obesity #diabetes sciencedirect.com/science/articl…

A single combined measure of hsCRP, LDL-C, and Lp(a) among initially healthy women was predictive of incident cardiovascular events over a 30-year period. All 3 biomarkers are modifiable thru either lifestyle or pharmacologic interventions #ESCCongress #cardiology #prevention

GMRx2 - Efficacy and safety of a novel triple single pill combination #ESCCongress #LBCT #ESCHotline #CVPrev 📍 will a single HTN med of 3 drugs improve BP control? 📍 telmisartan+amlodipine+indapamide 📍>50% 💃🏻👏🏽 🗝️: effective & safe $ weeks

🔥 A new therapeutic era in #HFpEF #FINEARTSHF with definitive evidence supporting the role of the non-steroidal MRA finerenone at #ESCCongress Now in NEJM nejm.org/doi/full/10.10…

nature.com/articles/s4159… Among nearly 19K patients across 3 high risk populations--FIDELIO-DKD, FIGARO-DKD, and FINEARTS-HF--finerenone reduced the risk of all-cause mortality by 9%. (HR 0.91; 95% CI 0.84-0.99; P = 0.027) Muthu Vaduganathan

Recalibration of risk score of cardiovascular disease for the Asia-Pacific population. Read more about the SCORE2 Asia-Pacific model in EHJ. doi.org/10.1093/eurhea… #CVD #ESCCongress #cardiotwitter European Society of Cardiology Journals European Society of Cardiology

Would love to see the threshold LDL mg/years (total plaque burden) for South Asian population for plaque rupture. Too long to wait for 5000 LDL-years! #Premature CAD Sarju Ganatra, MD, FACC Jaideep Alka Kanaya Priyanka Satish Anandita Agarwala Kulkarni, MD FACC Khurram Nasir Salim Virani Dinesh Kalra, MD Romit Bhattacharya

Wow! The popularity of #Jeopardy at the World Congresses is a testament to the tremendous efforts poured in by American College of Cardiology at the regional and the national levels #ACC conferences! More responsibilities for the next generation to take the show to the higher highs at #ACC25

Saurabh S Dani, MD, MSc Sarju Ganatra, MD, FACC Jaideep Alka Kanaya Priyanka Satish Anandita Agarwala Kulkarni, MD FACC Salim Virani Dinesh Kalra, MD Romit Bhattacharya Athero very heterogeneous and complicated process and trying to simplify as an easy concept as "LDL life years" is just not good science or policy Huge differences across the LDL years spectrum where folks develop at a lower threshold and never with highest lifetime exposure.

Congratulations to Dr. Rishi Wadhera on receiving 2 R01 grants totaling $6 million from the NIH for research focused on leveraging policy to advance cardiovascular health in United States.

Superb work by Lahey Cardiology stellar fellow Rushin Patel MD and fantastic collaborators led by Sarju Ganatra, MD, FACC !