Stratification of patients with AML using LSC score (LSC-17) is improved by the score associated with AP-1/TNF-α gene signature. ow.ly/CfF950Tkueu #myeloidneoplasia #hematopoiesisandstemcells

In utero hematopoietic stem cell transplantation for Fanconi anemia ow.ly/pN0q50Tkr8F #hematopoiesisandstemcells #immunobiologyandimmunotherapy #transplantation

New frameworks for hematopoiesis derived from single-cell genomics ow.ly/fVkR50TgBa3 #hematopoiesisandstemcells

A new model of extramedullary hematopoiesis ow.ly/wCrc50Ta0HP #hematopoiesisandstemcells

Emerging genetic technologies informing personalized medicine in Shwachman-Diamond syndrome and other inherited BMF disorders ow.ly/G55H50TeJxH #hematopoiesisandstemcells

Adrenal extramedullary hematopoiesis is associated to the formation of PDGFRα+LEPR+/− foci in mice and CXCL12+FOXC1+ stroma in humans. ow.ly/VyIp50Ta29k #hematopoiesisandstemcells

The inflammatory microenvironment that accompanies aging, and specifically TNF, favors TET2-mutant myeloid expansion. ow.ly/imKE50SXLug #hematopoiesisandstemcells #immunobiologyandimmunotherapy #myeloidneoplasia

BDCPs, including NBEA, LRBA, NBEAL1, and LYST, are required for efficient hematopoietic reconstitution after bone marrow transplantation. ow.ly/RIX950SXLpA #hematopoiesisandstemcells

Context matters: role of ATF4 in hematopoiesis ow.ly/NCJm50SYKez #hematopoiesisandstemcells

ATF4 directly regulates the transcription of Rps19bp1 to coordinate ribosome biogenesis and promote erythropoiesis. ow.ly/R67s50SYKtl #hematopoiesisandstemcells #redcellsironanderythropoiesis

Hit the road JAK, don’t P-STAT, stem more! ow.ly/a3Pi50SYK99 #hematopoiesisandstemcells

Substantial attrition of HSC function occurs within 24 hours of ex vivo culture independently of cell cycle progression. ow.ly/stos50SYKAO #hematopoiesisandstemcells #genetherapy

PBSC and BM donors had no differences in incidence rates for myeloid, lymphoid, other cancers, autoimmune diseases, or thrombotic events. ow.ly/5j0w50SX2GE #clinicaltrialsandobservations #healthservicesandoutcomes #hematopoiesisandstemcells #transplantation

Immature erythroblasts in pleural effusion: an initial presentation of acute erythroid leukemia in a patient with a history of MDS ow.ly/EvWW50SYJEr #bloodwork #hematopoiesisandstemcells #myeloidneoplasia

CRISPR/Cas9-mediated gene disruption determines the roles of MITF and CITED2 in human mast cell differentiation ow.ly/c52H50SX04l #hematopoiesisandstemcells

Donor safety confirmed ow.ly/NhoC50SWYOn #InsideBloodAdvances #IBAs #healthservicesandoutcomes #hematopoiesisandstemcells #transplantation

The deficiency of pseudouridine in mt-tRNAs due to PUS1 mutation contributes to impaired mitochondrial function and anemia in a patient with MLASA. ow.ly/HGCi50SU4fW #redcellsironanderythropoiesis #clinicaltrialsandobservations #hematopoiesisandstemcells

T cells from CH are deficient in GIMAP expression, suggesting CH may impair T-cell differentiation. ow.ly/erlv50SMw6l #immunobiologyandimmunotherapy #hematopoiesisandstemcells

Plasma cells’ fate: it is a complex “orchestra” ow.ly/jQFo50SPrk2 #hematopoiesisandstemcells

CD14+ monocytes from patients with CH stimulate inflammation through increased cytokine expression. ow.ly/uozj50SMuJe #immunobiologyandimmunotherapy #hematopoiesisandstemcells