Not so natural, not so killers ow.ly/BBri50Tr7sV #immunobiologyandimmunotherapy

Patients with MM patients have increased CD16/CD226Low NK cell subsets characterized by adhesion defects and reduced effector functions. ow.ly/ZF6T50Tr8n9 #immunobiologyandimmunotherapy #clinicaltrialsandobservations #lymphoidneoplasia #multiplemyeloma

Allogeneic hematopoietic cell transplant recipients are at risk of clinically significant viral infections due to lack of T-cell immunity. ow.ly/qV8H50Tkt6o #clinicaltrialsandobservations #healthservicesandoutcomes #immunobiologyandimmunotherapy

CAR-37 T cells expanded to >98% of T cells and led to complete responses but caused severe cytopenia associated with high levels of IL-18. ow.ly/b04o50TmsjI #clinicaltrialsandobservations #immunobiologyandimmunotherapy

The safety and efficacy benefits of ide-cel were proportionate in young and older patients despite frailty and geriatric characteristics. ow.ly/I9to50Tktui #immunobiologyandimmunotherapy

Therapy response in AML: a tale of two T cells ow.ly/mluJ50Tmrui #immunobiologyandimmunotherapy

The presence of CLL cells delays T-cell receptor–mediated CAR T-cell activation and impairs proliferation and restimulation. ow.ly/XXby50Tktp3 #immunobiologyandimmunotherapy #lymphoidneoplasia

Activation of the NLRP3 inflammasome during nutrient starvation results in excessive interleukin-1β production by XIAP-deficient cells. ow.ly/6vVX50Tms6X #immunobiologyandimmunotherapy

Single-cell RNA sequencing analysis reveals developmental dichotomic programs and clonal expansion in relation to therapy response in AML. ow.ly/Oe2F50Tmsec #immunobiologyandimmunotherapy

Conditioning with anti-CD47 and anti-CD117 plus JAK inhibition enables toxic payload-free allogeneic transplantation ow.ly/eRcJ50TkrAw #immunobiologyandimmunotherapy #transplantation

An important step in the BIRC4 forest ow.ly/slQA50TmrL2 #immunobiologyandimmunotherapy

In utero hematopoietic stem cell transplantation for Fanconi anemia ow.ly/pN0q50Tkr8F #hematopoiesisandstemcells #immunobiologyandimmunotherapy #transplantation

The rules of T-cell engagement: current state of CAR T cells and bispecific antibodies in B-cell lymphomas ow.ly/CXRr50TkrZB #drugadvances #clinicaltrialsandobservations #immunobiologyandimmunotherapy #lymphoidneoplasia

Prophylactic VSTs: a promising start but still work to do ow.ly/Pof950TkqOf #InsideBloodAdvances #IBAs #clinicaltrialsandobservations #healthservicesandoutcomes #immunobiologyandimmunotherapy #transplantion

TCR targeting hematopoiesis to cure leukemia ow.ly/VBjj50TgA9x #immunobiologyandimmunotherapy

Primary end points of feasibility and tolerability were met in a phase 1 clinical trial of HA-1 TCR-T for recurrent leukemia after HCT. ow.ly/6yCM50TgByb #immunobiologyandimmunotherapy #clinicaltrialsandobservations #transplantation

The prevalence of RBC abs increased from 2010 to 2021; RBC abs high risk for HDFN were identified in 74.3% of pregnancies. ow.ly/XZY550T8ME0 #transfusionmedicine #immunobiologyandimmunotherapy

Is the sun rising or is the sun setting? ow.ly/yTnI50TeJF8 #immunobiologyandimmunotherapy

VivoVec administration in nonhuman primates generates anti-CD20 CAR T cells in vivo, leading to prolonged complete B-cell depletion. ow.ly/HRuh50TeJv2 #immunobiologyandimmunotherapy #genetherapy

Tumor-associated macrophages repolarization and epigenetic regulators may open new therapeutic options for the fight against BL lymphoma. ow.ly/MYyM50T7NbP #lymphoidneoplasia #immunobiologyandimmunotherapy