Excited to see the final version out eLife - the journal. A long journey since the 1st draft as we ran experiments to test new model's predictions. Thanks to reviewers whose comments made it a better paper!
vizhe, A Pezzotta, ClopathLab
Image by julia kuhl at somedonkey.bsky.social
article: elifesciences.org/articles/86725…

The novel function of apical ICAM-1 in regulating bile duct homeostasis in the liver. elifesciences.org/articles/89261…

Researchers present a platform for cardiac tissue cultivation with 3D ring-shaped cardiac tissues generated from human stem cell-derived cardiomyocytes. elifesciences.org/articles/87739…

Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnels by stiffening the plasma membrane. elifesciences.org/articles/92078…

The ancestral function of Hippo pathway kinases in contractility and cell density in a unicellular ameboid closely related to multicellular animals. elifesciences.org/articles/90818…

A #CryoEM structure of VMAT2, a transporter in synaptic vesicles, reveals the mechanisms of drug and neurotransmitter binding, inhibition, and transport. elifesciences.org/articles/91973…

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Neutrophil recruitment in muscle blood supply.

SARS-CoV-2 spike proteins administered via the nose in mice can interact with macrophages in the lungs, which draws in neutrophils, contributing to lung #inflammation . #Covid #Immunology elifesciences.org/articles/86764…

A brain region called locus coeruleus helps mice remember out of the ordinary events by releasing the chemical dopamine. elifesciences.org/digests/91465/…

A new library of stem cells that express a fluorescent protein offers the opportunity to study the precise locations of thousands of human proteins in many different types of cells. elifesciences.org/digests/92819/….

Certain Leukemia cells can become resistant to cancer treatment without gaining new mutations, instead changing which parts of the DNA are active. elifesciences.org/digests/93019/…

🌱 December's most read Plant Biology paper addresses the earliest events that enable plant roots to reorient growth in response to gravity: elifesciences.org/articles/91523…

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A new AI framework could make it easier to match genes with certain human characteristics. elifesciences.org/digests/92574/….

Cell migration in the neural crest is controlled by a proteolytic pathway that involves a double inhibition mechanism. elifesciences.org/articles/91864…

An enzyme that remodels the cell wall of the gut bacterium E. faecium helps them enhance the immune response against cancer. elifesciences.org/articles/97277…

#Ketamine has emerged as one of the most promising therapies for treatment-resistant #depression , but individual results vary significantly. Researchers are trying to understand what this means for patients. elifesciences.org/articles/84173….

Examining the role of non-coding RNAs in liver treatment. elifesciences.org/digests/91438/….

A tool for finding proteins with a chemical modification linked to cognitive health in fruit flies reveals how the process could affect learning in response to smell. elifesciences.org/digests/91269/….

The origins of RNA viruses can be hard to trace. This #ReviewedPreprint considers a more recent origin for coronaviruses and suggests their diversification occurred mainly through host switching rather than diversification with hosts. elifesciences.org/reviewed-prepr…