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Selective digestive tract decontamination in adults with acute brain injuries on MV in #ICU, post hoc analysis of SuDDICU 🇦🇺 RCT 💊SDD vs standard care significantly reduced in-hospital/ICU mortality & ventilator/ICU/hospital-free days to day 90 #FOAMcc 🖇️rdcu.be/drCdp

Great to see ANZMUSC led trials recognised at the annual #Acta2023 clinical trial of the year award.

The Suddicu study trial led by The George Institute for Global Health finalist of the ACTA: Australian Clinical Trials Alliance clinical trial of the year award

*Something new is coming!* ICTU is hosting its 1st Contemporary Clinical Trials Methodology Meeting with a difference for trial statisticians 🗓️SAVE THE DATE 25th April 2024🗓️ Speaker announcements and registration details coming soon!

Thinking of doing a SWAT? Here's a list of 11 priority SWAT questions from the York Trial Forge SWAT Centre: trialforge.org/2024/02/list-o…

Our back@home protocol is now online!

Delighted to announce the speakers for the 1st ICTU & NIHR RSS Imperial & partners Hub Trial methodology meeting - 25th April - registration opening soon! We cant wait to hear from these great speakers!

Registration is now open to attend ImperialCTU & NIHR RSS Imperial & partners Hubs' 1st Contemporary Clinical Trials Methodology Meeting! Register today here: imperial.ac.uk/events/174911/…

We have an exciting agenda instore with these fabulous speakers lined up to talk about Group Sequential Trial Designs, Response-Adaptive Randomisation and Sample Size Re-estimation across three main sessions. Registration link below👇

Check out this newly published special issue focused on cluster randomised trials. It covers everything from ethics, design, analysis and practical implementation issues. All open access 🌟 sciencedirect.com/journal/journa… #clinicaltrials #clustertrials

📊Calling all trial statisticians & statistically minded trialists/clinicians curious about adaptive designs!📊 Don't miss the 1st Contemporary Clinical Trials Methodology Meeting from ImperialCTU & NIHR Research Support Service (RSS) Imperial and Partners Hubs. Register now! imperial.ac.uk/events/174911/…

✏️Register for our contemporary clinical trials methodology meeting on 25th April & you’ll hear from Laurent Billot discussing “the potential for group sequential designs to allow simple trial adaptations while bringing substantial efficiency benefits. " bit.ly/3UcQVX5

One of the primary elements that should form part of a well-conducted clinical trial is the statistical analysis plan or #SAP 1/7 #MethodologyMonday #84

Check out this video glimpse into our recent 'Contemporary Clinical Trials Methodology Meeting' event! 🎥 It was a great day, and we can't wait for the next one! 💫 #CCTMM2024 #ClinicalTrials #Methodology

Thoroughly enjoyed the 1st ICTU & NIHR RSS Contemporary Clinical Trials Meeting last week! #CCTMM24 Thanks to all our wonderful speakers...inspired about interim analyses thanks to Leila Laurent Billot & Stuart Pocock

INTERACT4 results presented now at #ESOC2024⏩ hyperacute blood pressure lowering shows benefit on functional outcome and on hematoma growth in ICH, but not in ischemic stroke or TIA. Room for implementation with mobile SU? European Stroke Org @nejm

In the INTERACT4 trial involving 2404 patients with acute stroke and elevated blood pressure, ambulance-delivered systolic blood-pressure reduction did not result in better functional outcomes than usual care. Full trial results: nej.md/3ysx39I #ESOC2024

Joel Dulhunty and Jason Roberts join JAMA Deputy Editor Preeti Malani to discuss the BLING trial that assessed continuous vs intermittent β-lactam antibiotic infusions in patients with sepsis or septic shock. Hosted on @amaedhub. ja.ma/3xlvmuz #CCR24

Presented at #CCR24: In a randomized trial involving patients undergoing invasive ventilation, pantoprazole decreased the risk of upper gastrointestinal bleeding as compared with placebo but did not affect mortality. Read the full REVISE trial results: nej.md/3KD01Xp

It is such a privilege to work with the amazing The George Institute for Global Health critical care team. Thank you @JAMyburgh A/Prof Naomi Hammond Simon Finfer for many years of collaboration and great work!