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A new study finds a novel #mechanism of EGFR-TKIs resistance in #lung cancer. Read about the role of GSTO1 in this process! 📖 nature.com/articles/s4138…

A new article published provides a mechanistic understanding of the favorable responses to PARPis in SLFN11-expressing and BRCA-deficient #ovarian tumours. Read more | nature.com/articles/s4138…

New study shows that PIM1 plays important role in macrophages polarization and chemotaxis in #NSCLC Read more ➡️ 🔗 nature.com/articles/s4138…

Circular #RNA may be a novel therapeutic target and prognostic biomarker in #gastric cancer! An example is circPAK2 described to regulate VEGFA-mediated gastric cancer metastasis! Read more 🔗 nature.com/articles/s4138…

How could neuronal cells help #cancer cells invade? Read about the mechanism of #perineurial invasion in #pancreatic cancer! nature.com/articles/s4138…

Want to read papers on a specific topic? Glance at our Collection #articles and learn more about #ferroptosis or #N6methyladenosinemethylation! 📖 🔬🧫🧪 nature.com/onc/collection…

Gastric cancer #liver metastasis shows impaired NK cell function, revealed by single-cell RNA #sequencing! Read more in the new article 🔗 nature.com/articles/s4138…

A new study shows how GATA2 plays a role in anticancer immunity and resistance in #prostate cancer! Read about the underlying mechanism 🔗 nature.com/articles/s4138…

How can #cancer-associated fibroblast facilitate angiogenesis in the #tumor microenvironment? Read more to find out! 🔗 nature.com/articles/s4138…

Targeting Snai1 in the tumour endothelium increases drug response and reduces #metastasis. 🔬nature.com/articles/s4138… Erik Henke #OpenAccess

Could GLI1 inhibitors be effective in the treatment of #BRCA1-deficient tumours? You can read more about the role of GLI1 in enhancing the DNA damage repair capacity here: nature.com/articles/s4138…

Check our latest issue for an overview of the current understanding of RHNO1, including its structure, function in the #DNA replication stress response, and role in DNA repair. nature.com/articles/s4138… University of Nebraska Medical Center

Increased expression of PrPC in EGFR-mutated #NSCLC promotes EMT and resistance to EGFR tyrosine kinase inhibitors - could circulating PrPC be a novel biomarker to monitor lung cancer evolution? nature.com/articles/s4138… Mouillet-Richard Sophie Sorbonne Université

A study improving our understanding of the mechanistic basis behind drug resistance in oesophageal #cancer. 🔬nature.com/articles/s4138… #ESCC #CancerResearch

Combined use of farnesyltransferase inhibitors and MEK inhibition is a promising strategy for HRAS-mutant tumours. 🔎nature.com/articles/s4138… Aradhya Nigam, MD Walid Chatila Alan Ho Niki Schultz

New #OpenAccess study from Martinez Lab highlights the translational potential of Jumonji KDM inhibitors against small cell lung cancer. nature.com/articles/s4138… #LungCancer #CancerResearch #SCLC

In our latest issue, Alexandre Bruni-Cardoso & co-workers identified an MST2 transcript variant that is mostly expressed in tumour samples and lacks quiescence and cell death-inducing activities. nature.com/articles/s4138… #CancerResearch

One step closer towards finding new effective drug treatments for meningioma and schwannoma. nature.com/articles/s4138… Clemens Oliver Hanemann Sylwia Ammoun

Choline metabolism leads to epigenetic reprogramming of SE-driven transcription factor KLF5 to facilitate #HCC development. Fudan University researchers describe how 🔬🧪 🔗nature.com/articles/s4138…

A new article by Ayesha Shafi, PhD lab discovers transcriptional co-activator CPB/p300 as a key mediator of DSB repair that modulates #genome integrity and promotes #castration-resistant #prostate cancer. Read more 📖 nature.com/articles/s4138…