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The researchers analyzed data from 14,328 adults treated with ICIs. brnw.ch/21wMEyM

Adjuvant treatment with apalutamide plus ADT might improve outcomes for patients with high-risk localized prostate cancer who have undergone radical prostatectomy. brnw.ch/21wMFHn #pcsm

Trimodal therapy consisting of radiation plus chemotherapy and transurethral resection is an effective potential alternative to radical cystectomy for high-grade T1 bladder cancer. brnw.ch/21wMFMi #blcsm

Adding the novel endogenous filtration markers β2-microglobulin and β-trace protein can improve the accuracy of glomerular filtration rate (GFR) estimation in patients with solid cancers. brnw.ch/21wMGFd #kidney #blcsm

The magnitude of PSA decline at 12 weeks after lutetium-177-PSMA-617 treatment initiation predicts long-term outcomes in patients with metastatic castration-resistant prostate cancer (mCRPC). brnw.ch/21wMGKs #ProstateCancerAwarenessMonth #pcsm

PSMA PET/CT enables more accurate staging of #prostatecancer in patients with BCR after primary treatment and is better at predicting pathologic outcomes after robotic prostatectomy compared with mpMRI. brnw.ch/21wMGQE #ProstateCancerAwarenessMonth #pcsm

Nephron-sparing surgery may not reduce the risk for later #kidney failure in patients with kidney cancer and stage 4 CKD. brnw.ch/21wMIvK #kcsm

Software providing personalized ESA dosing increased the rate of target hemoglobin attainment compared with standard of care in patients with hemoglobin variability while on dialysis. brnw.ch/21wMINX

Certain autoantibodies were significantly associated with neuropsychiatric manifestations of systemic lupus erythematosus, emphasizing their utility for accurately diagnosing and managing this complex condition. brnw.ch/21wMIU0

Ocular manifestations are common among patients with all types of antineutrophil cytoplasmic antibody-associated vasculitis, and machine learning-based predictive models offer potential for early detection and personalized treatment. brnw.ch/21wMIXW

Once-weekly efsitora is noninferior to once-daily degludec for reducing glycated hemoglobin levels in adults with type 2 diabetes who have not received insulin. brnw.ch/21wMJ25

Elevated interleukin-6 levels were linked to an increased risk for obesity-related cancers among patients with newly diagnosed type 2 diabetes. brnw.ch/21wMJ5N

More than half of adults with uncontrolled hypertension are unaware that they have hypertension. brnw.ch/21wMKpt

Treatment with tirzepatide, compared with glucagon-like peptide 1 (GLP-1) receptor agonists, is associated with lower risks for mortality, cardiovascular events, and kidney events among patients with type 2 diabetes. brnw.ch/21wMKxj

Two complementary ultrasound procedures, Break Wave™ lithotripsy (BWL) and ultrasonic propulsion, show promise for treating #kidney stones in office with minimal anesthesia. brnw.ch/21wMKJ5

Chronic pain at multiple sites is associated with an increased risk of cardiometabolic multimorbidity. brnw.ch/21wMKW6

For patients with obesity receiving semaglutide or liraglutide, weight reduction at 1 year is associated with medication active agent, dosage, treatment indication, and persistence of coverage. brnw.ch/21wML3R

Individuals with comorbid depression and diabetes have double the risk for all-cause mortality than those without depression. brnw.ch/21wMLbq

The Centers for Medicare and Medicaid Services has proposed a 2.8% reduction in the Physician Fee Schedule conversion factor for 2025 that could threaten the financial viability of independent urology practices. brnw.ch/21wMLfr

Inhibition of cathepsin C showed promise as a therapeutic strategy for reducing neutrophil activation and neutrophil-mediated inflammatory diseases in animal and in vitro models of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). brnw.ch/21wMLkr