Twitter Beğeni Hilesi

Excited to share our new paper on experimental and computational methods for studying #DNAmethylation with Infinium arrays in low-input samples, even single cells! We dived into the nuances of chromatin states and germ cell development. doi.org/10.1093/nar/gk…

#NewNProt from Yi Xing and colleagues at CHOP Research, for discovery and quantification of #alternativesplicing events from large-scale #RNAseq data with rMATS-turbo bit.ly/3wuLDg1

A pleasant surprise to start the day! Our article on TEQUILA-seq, a versatile and low-cost method for targeted long-read RNA sequencing, has made it into Nature Communications's Top 25 life and biological sciences articles of 2023! #NCOMTop25 CHOP Research nature.com/collections/di…

DNA methylation dynamics and dysregulation delineated by high-throughput profiling in the mouse Top cited paper from Cell Genomics - 20 citations hubs.ly/Q02m-Mg50 Wanding Zhou Children's Hospital Peter W. Laird Hui Shen Van Andel Institute (VAI)

Happy to share our new study Nature Communications! In collaboration with Dr. Yanzhong Yang City of Hope, we show that loss-of-function mutation in protein arginine methyltransferase 9 (PRMT9) causes abnormal synapse development by dysregulation of RNA splicing. nature.com/articles/s4146…

Looking forward to it!

Very much enjoyed my visit to St. Jude to speak at the Danny Thomas Lecture Series, on long-read RNA-seq strategies to study cancer and rare genetic diseases!

IOTN SC Chair Dr. Alan Hutson oldbiostats from Roswell Park delivers an overview of the IOTN network, including its history & impact, as well as the goals & accomplishments of the Data Management & Resource Center, which has facilitated collaboration among IOTN funded components.

Dr. Zhiyuan Mao from UCLA shares their work isolating T cell receptors that target cancer-enhanced splicing events in small-cell carcinoma using nanovials. #IOTNCapstoneMeeting

🚀Excited to share our latest preprint on the Methylation Screening Array (MSA) design to facilitate human EWAS discoveries. MSA leverages previous EWAS, bulk, single-cell WGBS data, and technologies for ultra-high throughput profiling. Checkout details: biorxiv.org/cgi/content/sh…

Excited to co-edit this upcoming Genomics Proteomics Bioinformatics Special Issue on "Long-read Sequencing", with Hui Shen and Wanlu Liu! Detailed information below. 👇

The 9th Annual MidAtlantic Bioinformatics Conference will be on Friday, October 4, 2024! Register now: midatlanticbioinformatics.org