Congratulations to new UIPS PI's Kelly Stecker and Bas van Ravensteijn for receiving prestigious grants uu.nl/en/news/person… Pharmaceutics Utrecht HeckLab

Mehman Bunyatov of The Boons Group developed a strategy for making HNK glycans. Backbone were prepared using enzymes, then chemical modifications. This is a reversal from what’s normally done in chemoenzymatic glycan assembly. You wanna coin a new term, Mehman? Utrecht Institute for Pharmaceutical Sciences Faculty of Science, Utrecht University

Fantastic to have this out! Great work from Donna Debets and Kelly E. Stecker in collaboration with Esther Lips and others from The Netherlands Cancer Institute. Faculty of Science, Utrecht University Utrecht Institute for Pharmaceutical Sciences X-omics Cell Reports Medicine: cell.com/cell-reports-m…

Now published in JACS Au! 6-O-sulfotransferase specificities! Great work by Yunfei Faculty of Science, Utrecht University Utrecht Institute for Pharmaceutical Sciences CBDD (Chemical Biology & Drug Discovery) pubs.acs.org/doi/full/10.10…

Analytical #glycotime! If you are interested in analyzing O-acetylated sialoside-containing glycoproteins with precision, differentiating all O-Ac positional isomers, take a look at this one from The Boons Group. nature.com/articles/s4146… Utrecht Institute for Pharmaceutical Sciences Faculty of Science, Utrecht University

Very happy to see this Review on the current status & future of PISA for drug delivery published in the Journal of Polymer Science! Many congrats to Eleonora G. Hochreiner for this beautiful and inspiring (first!) paper. Pharmaceutics Utrecht, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University doi.org/10.1002/pol.20…

Interested in the fascinating field of microproteins? Join my group in a collaboration with Sebastiaan van Heesch at the PMC. PostDocs apply below: werkenbijprinsesmaximacentrum.nl/en/vacancy/pos… HeckLab PrinsesMáximaCentrum

Dario Cramer HeckLab Utrecht Institute for Pharmaceutical Sciences identified, together with Monash University, a novel intermediate in the plasminogen conversion to plasmin. These findings help to better understand the plasminogen-plasmin system, involved in the control of fibrin degradation mcponline.org/article/S1535-…

Very happy to see our latest review on PISA for drug delivery (doi.org/10.1002/pol.20…) highlighted on the cover of Journal of Polymer Science! Many credits to Eleonora G. Hochreiner for leading the writing process & designing the cover! Pharmaceutics Utrecht Utrecht Institute for Pharmaceutical Sciences Faculty of Science, Utrecht University

Christmas came a little early in our lab Pharmaceutics Utrecht, Utrecht Institute for Pharmaceutical Sciences! Brand new Leica Microsystems confocal set-up dedicated for Fluorescence Correlation Spectroscopy! Made possible by European Research Council (ERC). Looking forward to start my #ERCStG project in 2024 & take this microscope for a spin!

Assymetry for the win! 10+ years of N-glycan synthesis and here we demonstrate that human influenza A viruses preferentially bind to the the a3 arm! #glycotime pubs.acs.org/doi/10.1021/ja…

Many new cancer drugs in the EU lack clear proof of added benefit. But still nearly all those drugs manage to recover their substantial research and development (R&D) costs relatively quickly after approval. Utrecht Institute for Pharmaceutical Sciences #healthcare #costs uu.nl/en/news/many-n…

Very relevant articles: Many new oncology drugs approved in the EU lack proof of added benefit uu.nl/en/news/many-n…

The master thesis of Luc Krimpenfort evolved into this review>> 𝗧𝗵𝗲 𝗙𝗗𝗖: 𝗔𝘁 𝘁𝗵𝗲 𝗴𝗲𝗿𝗺𝗶𝗻𝗮𝗹 𝗰𝗲𝗻𝘁𝗲𝗿 𝗼𝗳 𝗮𝘂𝘁𝗼𝗶𝗺𝗺𝘂𝗻𝗶𝘁𝘆? heesters.gitlab.io/reviewcellrepo… With invaluable help of Søren Degn! Cell Reports Utrecht Institute for Pharmaceutical Sciences doi.org/10.1016/j.celr…

Another chapter of Yunfei published. We got some real chemoenzymatic synthesis of kerstan sulfates for you pubs.acs.org/doi/10.1021/ja… The Boons Group CBDD (Chemical Biology & Drug Discovery) Utrecht Institute for Pharmaceutical Sciences

The 2024 Advanced Functional Polymers for Medicine Conference will take place at Utrecht Institute for Pharmaceutical Sciences, June 5-7! Discover the latest developments in polymer-based systems for drug delivery, regenerative medicine & diagnostics. Info & registration (limited spots!): uu.nl/en/research/ad…

Last Friday Marc Falandt joined UniStem Day 2024 Utrecht University to share our lab's work European Research Council (ERC) #Volumebio and his research experience! So nice to see all the curiosity and interest from the high school students present #STEMeducation #Unistemday2024 thanks Utrecht Institute for Pharmaceutical Sciences for organizing

Very much appreciate the outcome of the ERC Advanced Grant evaluation chosing to grant my REVAMP proposal European Research Council (ERC) . Thanks HeckLab making this possible, and our collaborators. Now we can push our ideas on #antibodies even further. Bijvoet Centre Utrecht Institute for Pharmaceutical Sciences Faculty of Science, Utrecht University

I'm happy to share that Luc Krimpenfort and myself have taken an active role in the Infection & Immunity UMC Utrecht graduate school as members of the PhD platform (Luc) and the board (myself). If you are a I&I PhD candidate, especially at Utrecht Institute for Pharmaceutical Sciences, hit us up for a chat! heesters.gitlab.io/ii_board