#ICYMI
Our NEW issue is now live!
Read it here: go.acs.org/99E

Supplementary cover story by Dr Laura Sanchez & Lu Wei UC Santa Cruz Science go.acs.org/99F

“Blue Light, Camera, Action!”

NEW #FirstReactions by Olof Idevall-Hagren & Paul O’Callaghan Uppsala University discussing the recent work by Jeremy Baskin Julia Xiang-Ling Li Reika Tei Masaaki Uematsu Weill Institute for Cell & Molecular Biology CornellChemistry #lipidtime go.acs.org/99D

Read it here: go.acs.org/99C

A DC electric field can be used to stick metals or graphite to soft materials including gels, animal tissues, fruits, & vegetables. Such electroadhesion is reversible & even works underwater

NEW #ASAP by Srinivasa Raghavan & team Univ. of Maryland
Read here: go.acs.org/98B

Pyrazinone Biosynthesis and Signaling─Myxo Style

NEW #FirstReactions by Sandra Loesgen (loesgenlab.bsky.social) & Rudolf Lab discussing work by Changsheng Wu, Wei Zhang, Yue-Zhong Li & team #ShandongUniversity go.acs.org/97B

Read it here: go.acs.org/97A

Our NEW issue is now live!
Read it here: go.acs.org/95Y

Front cover story by Tao Zhang & co-workers at Ningbo Institute of Materials Technology and Engineering go.acs.org/95Z

Ji and co-workers develop 5-BrUrd-modified tRNA activity-based probes to study the molecular basis of dihydrouridine formation by hDUS2 and screen small molecule inhibitors KleinerLab Princeton Chemistry

NEW #ASAP
Read it here: go.acs.org/95A

Flipping the GPCR switch: CarreiraGroup Roman Sarott report generalizable structure-guided ligand modification transforming a Cannabinoid Receptor 2 agonist into an inverse-agonist

NEW #ASAP
Read it here: go.acs.org/94x

Design of cytotoxic T cell epitopes for enhancing antigen processing and presentation, enabled by machine learning of human degrons and cytosolic delivery with two anthrax proteins

NEW #ASAP by PenteluteLab RGB Lab @ MIT & team
Read it here: go.acs.org/93q

A Large Open-Source Zeolite Synthesis Dataset Enables Machine Learning Rationalization of Zeolite Structure-Synthesis Relationships

NEW #ASAP by DMSE at MIT Olivetti Group @ MIT RGB Lab @ MIT MIT ChemE Dept Román Lab @ MIT ITQ (UPV-CSIC)
Read it here: go.acs.org/92l

Nominations are open for C&EN’s Trailblazers until April 30. This year, we will feature Hispanic and Latina/e/o chemists. Find out more about the project and nominate your favorite molecular scientists here: cenm.ag/nominatetrailb…

Thiol-mediated uptake (TMU) is an intriguing enigma in current chemistry and biology. Our new paper in ACS Central Science provides a solid basis to understand TMU, enable and prevent entry into cells along at least three orthogonal dynamic covalent networks

pubs.acs.org/doi/10.1021/ac…

Molecular Deformation Is a Key Factor in Screening Aggregation Inhibitor for Intrinsically Disordered Protein Tau

NEW #ASAP by Tianming Yao & team #TongjiUniversity
Read here: go.acs.org/917

A substrate-selective biocatalytic strategy is used to discriminate between two intermediates in equilibrium, subsequently directing a cyclization step to arrive at tricyclic azaphilone natural products

NEW #ASAP by Alison Narayan & team
Read it here: go.acs.org/8YI

A hybrid approach mixing physics-based and data-driven methods is used to predict the electronic excitations of small (and large!) molecules

NEW #ASAP by the joint collaboration of COSMO Lab and Molecolab Pisa
Read it here: go.acs.org/8XA

Magic sized clusters are ubiquitous intermediates in quantum dot synthesis. Brandi M. Cossairt & team UWChemistry isolate and structurally characterize an InAs nanocluster with a composition of In26As18(O2CR)24(PR'3)3.

NEW #ASAP
Read it here: go.acs.org/8Wa

#ICYMI
Our NEW issue is now live!

Supplementary cover story by Hao Gao, Xin-Luan Wang & team #JinanUniversity go.acs.org/8W9

Leveraging a Phage-Encoded Noncanonical Amino Acid: A Novel Pathway to Potent and Selective Epigenetic Reader Protein Inhibitors

NEW #ASAP by Wenshe Ray Liu, J. Trae Hampton, & team Texas A&M University. Read it here: go.acs.org/8V0

Automated Flow Peptide Synthesis Enables Engineering of Proteins with Stabilized Transient Binding Pockets

NEW #ASAP by TU Darmstadt (@Hausch_lab) 's Twitter Profile">Structure based drug research TU Darmstadt & team TU Darmstadt
Read it here: go.acs.org/8U7

Rapid droplet movement on surfaces using newly designed photo-responsive surfactants with fast switching kinetics for heat transfer and microfluidics applications

NEW #ASAP by Yangying Zhu, Read De Alaniz group, Paolo Luzzatto-Fegiz & team
Read it here: go.acs.org/8Sf

Sebastien Vidal ACS Central Science For those new to the #vidalized #glycotime mission, please read this great 2021 interview with Sebastien Vidal ACS Central Science:

pubs.acs.org/doi/10.1021/ac…