Wow. Glucocorticoid-induced metabolic and transcriptomic changes - itaconate as a critical immunomodulatory metabolite nature.com/articles/s4158…

We investigated the contributions of renin-independent & ACTH-mediated aldosteronism in individuals with low-renin phenotype representing an entire continuum of BP. Thank you @AnandVaidya1 Jen Brown, our team members/collaborators SS endo CU Adina Turcu doi.org/10.1210/clinem…

Thrilled to share our publication “Association of Albuminuria With Chronic Kidney Disease Progression in Persons With Chronic Kidney Disease and Normoalbuminuria: A Cohort Study” in Annals of Int Med Anand Srivastava Sophie Claudel, MD acpjournals.org/doi/10.7326/M2…

'remission' should replace 'cure'

'the findings deconstruct the classical equivalence of lateralized PA with unilateral PA - we illustrate that lateralized PA can arise from multifocal CYP11B2 areas, at various stages of development, which might be present in 1 or both adrenals'

Nice write up of the Circulation paper ahajournals.org/doi/10.1161/CI… in the The Ottawa Hospital weekly news
Remi Goupil Anand Vaidya et al
Lead by Greg Hundemer

Society members are invited to review and provide feedback for our new joint clinical practice guideline, Diagnosis and Therapy of Glucocorticoid-Induced #AdrenalInsufficiency , which they received via email. The comment period will close on February 21. European Society of Endocrinology (ESE) (1/2)

our attempt at shifting the focus from sodium to potassium in hypertension

review in the American Journal of Hypertension, lead by Sriram Sriperumbuduri with help from Paul A Welling,@[email protected] and others

now with a free link (not sure how long it will work) academic.oup.com/ajh/article/37…

Super important for decision making and clinical management. Deconstructing the dichotomy of primary aldosteronism: even when it lateralizes, it may still be bilateral, owing to diffuse, multifocal, somatic mutations

Full link: ahajournals.org/doi/10.1161/HY…

A small step, but in the right direction- towards improving the detection of #PrimaryAldosteronism , a common, but overlooked form of #Hypertension . JAMA Internal Medicine U-M Department of Internal Medicine

Exactly

jamanetwork.com/journals/jama/…

Thanks to everyone for joining- over 200 registered and ~100 joined live. Links to the Recording should be sent out to all who registered.

Some highlights from the talk:
1. If clinically looks like PA, don't exclude based on arbitrary cut-points.
...

…even in normotensive people…

Primary aldosteronism is not a “secondary” cause of hypertension

I just registered (takes only 5 seconds 👇) for this great seminar with an update about #Primary Aldosteronism with experts Adina Turcu Anand Vaidya Jordy Cohen, MD, MSCE Laboratory of Vivek Bhalla, MD- Stanford 🫀

With CARTaGENE data, we show Subclinical PA is linked to worse central BP, PWV, adverse cardiac remodeling and incident
hypertension, all independent of BP. Excellent work from Greg Hundemer and co-authors! Anand Vaidya Swapnil Hiremath @[email protected] Manish M Sood MD

ahajournals.org/doi/10.1161/CI…

Beautiful study!
I await the day we can drop “subclinical”, drop the arbitrary thresholds and maze of diagnostics currently recommended, and appreciate that PA pathophysiology ranges across the entire continuum of renin-independent aldosteronism, ergo simplifying recognition & tx

Beautiful study!
I await the day we can drop “subclinical”, drop the arbitrary thresholds and maze of diagnostics currently recommended, and appreciate that PA pathophysiology ranges across the entire continuum of renin-independent aldosteronism, ergo simplifying recognition & tx

Welcome back to #AJHTweetorials

Let’s talk about medical management of primary aldosteronism (PA) in this edition

Check out this review from Anand Vaidya and colleagues for background academic.oup.com/ajh/article-ab…

1/

Calling all adrenophiles! Save the date! Formally the adrenal cortex meeting, now the international adrenal meeting. (Adding the medulla!) May 29-31, 2024 in Boston, MA, USA. All the latest adrenal science. See you there! #adrenal European Network for the Study of Adrenal Tumours

Register today to join mods 𝙼𝚊𝚝𝚝 𝙻𝚞𝚝𝚑𝚎𝚛 on behalf of Hypertension and @councilonHTN SCILL for a #HypEdSeries Webinar with @anandvaidya17 Adina Turcu Jordy Cohen, MD, MSCE Laboratory of Vivek Bhalla, MD- Stanford

Dec 12, 20:00-21:00 UTC

Primary Aldo: Screening and Interpretation

REGISTER: ahajrnls.org/3sFNE7u