Big thanks to Professor Johan Auwerx Auwerx Lab for the insightful talk on mitochondria & aging at Kinderspital Zürich. We enjoyed that you highlighted the power of mouse data to enable human health trajectories. Your expertise in metabolism and genetics has left us inspired 🧬

🚀New #Celegans study alert! We presented at #TAGC24 novel data produced by our laboratory system SydLab™ One for the new collaborative study with Auwerx Lab EPFL and Arwen Gao Amsterdam UMC
Missed the session? Download the poster here 🔗nagibio.hubspotpagebuilder.com/tagc24-poster-… #inwormwetrust

Another step in understanding the role of sphingolipids and ceramides in muscle function. Congrats to Martin and the team. doi.org/10.7554/eLife.… eLife - the journal

Breakthrough functional outcome from our Phase 1b #clinicaltrial of RJx-01 in #sarcopenia reveal:
💪 Improved muscle strength
🏃 Improved muscle function
🥵 Improved fatigue resistance
Full press release: ow.ly/CEob50QG03C
#aging #biotech #clinicaltrial s #healthyaging

Excited to present to you our latest study (Auwerx Lab Coon Lab Nagi Bioscience) using worm genetic reference population to study factors that influence lifespan. biorxiv.org/content/10.110…
A short audio summary: sciencecast.org/casts/1vdqe2bs…
😃

Very thoughtful thinking of Jens Eckstein from Hevolution about aging and geroscience podcasts.apple.com/us/podcast/ep1…

Online now! Mitophagy in human health, ageing and disease dlvr.it/SzYzGg

Our review 'Mitophagy in human health, ageing, and disease' just got published in Nature Metabolism!

A dream team of scientists made this possible. Thanks to Luigi Ferrucci, head of the The National Institute on Aging (NIA) , Auwerx Lab EPFL, Anna Picca and Julie Faitg, Ph.D..

rdcu.be/dsrzL

A collaborative literature review between Amazentis, NIH and our lab highlights the role of mitophagy in disease

Congratulations to Andrea Ablasser, Johan Auwerx (Auwerx Lab), and Michele De Palma who have been included in Clarivate's Highly Cited Researchers! actu.epfl.ch/news/three-sv-…

#HighlyCited2023 #highlycitedresearchers #EPFL

Honoured to announce that the Society for Endocrinology has awarded Kristina Schoonjans the 2023 European Medal for her work on #bileacid signalling #SfEBES2023 . Thanks to all our collaborators and colleagues who have contributed to this achievement!
endocrinology.org/endocrinologis…

We welcome to our team Ioanna Daskalaki and Saman Sharifi as post-doctoral scientists and Anna, German, Mert, and Veronika as student assistants.

Again in 2023, we were selected as a 'Highly Cited Researcher”. Thanks to all @Auwerx_lab graduates for the hard work that enabled our continued success! webofscience.com/wos/author/rec… #HighlyCited2023

METABOLIC MESSENGER

Alessia Perino & Schoonjans Lab (@epflSV, EPFL) summarize the most recent literature on the receptor-mediated role of bile acid signaling in controlling peripheral & central energy homeostasis.

Nature Metabolism #Meded #MedTwitter

nature.com/articles/s4225…

Today we announced Ph 1 data for TLC-2716, a liver-targeted LXR inverse agonist in development for severe hypertriglyceridemia/ #NASH , to be presented at #AHA23 . The data demonstrate dose-dependent improvements in plasma TGs, LDL-C, LDL particles and apoB. bwnews.pr/3sweuii

Congratulations to OrsoBio for the completion of the series A financing! It will help in bringing ACMSD inhibitors one step closer to the clinic. orsobio.com/orsobio-announ…

Thanks for the invitation. On the 7th of November, we are gathering the growing scientific community studying the postbiotic #Urolithin A in a virtual Scientific Summit.

The event is now open for registration and abstract submission
urolithinasummit.broadcastmed.io

Congrats to Terytty Lab Qi Wang Arwen Gao and our team on this fundamental study uncovering the mechanism on how the lysosomes mediate the communication from stressed mitochondria, but not ER, to the nucleus through mTORC1-dependent ATF4 phosphorylation nature.com/articles/s4142…

Glad to have our collaboration with Farooqi Lab out in Cell Reports Medicine!

We leveraged #CNVs in 🇬🇧 UK Biobank and 🇪🇪 Estonian Biobank to study the adult clinical trajectory of the obesity-related gene SH2B1’s LoF. Key findings in 🧵👇🏻

#genomics #metabolism #T2D

tinyurl.com/3ys5jxfj

🟪NEW Article in press❕

Cyclo (His-Pro): a further step in the management of #steatohepatitis

🔓 #OpenAccess at👉bit.ly/3OjGpZO

#LiverTwitter