Komen grantee BalkoResearchLab presents his work on understanding and improving #breastcancer response to immunotherapy @ #AACR24 . To learn more, check out the MBC Impact Series where he discussed his work: bit.ly/4cFtpsN

This is no joke! On April 1, the HTIP and TRIO Vanderbilt-Ingram Cancer Center programs will host its 2nd Annual Retreat in📍214 Light Hall from🕐1-5pm.

Eager to host Liza Makowski Lab & Gregory Lesinski as our external keynotes alongside Krishnendu Roy, Eben L Rosenthal, MD, Emily N. Arner, Ph.D., & Julia Steele!

So proud of this outstanding scientist and person Brandie Taylor defending her thesis today. A Susan G. Komen ASPIRE scholar, Cancer Discovery Journal for ImmunoTherapy of Cancer published author and all around superstar. Can't wait to see what the future holds!! VUMC Research Vanderbilt School of Medicine Basic Sciences

This line up!!! Phenomenal. Society for Immunotherapy of Cancer Spring Scientific. Happening NOW!

I am defending my dissertation next week on March 15th! Grateful for the mentorship by BalkoResearchLab !
DM me if you would like the zoom link.

Rock.Star. Great talk with wonderful implications for the next generation of myeloid therapy in ccRCC. Can’t wait to see what you do next!

From the latest issue—
#NKG2A is a Therapeutic Vulnerability in #Immunotherapy Resistant MHC-I Heterogeneous Triple Negative #BreastCancer , by Brandie Taylor, Xiaopeng, BalkoResearchLab et al.
bit.ly/49WMp43
Vanderbilt University Medical Center #TNBC

Super excited for next year's meeting! Only 290 days and counting (OK you got me... I didn't do the math I just guessed 😂)

Excited to see the *official* version out!!! Great job by the editorial staff... It looks phenomenonal!

Don't miss today's double feature seminar!
- Special #VI4Seminar with Christian Meyer from CU Boulder 🦬!
🗣️ 'A high throughput, low waste viability assay for microbiology'
- #MPTSeminar with Elizabeth Wescott (@BalkoLab)
📆 2/15 (TODAY!)
🕥 1:00pm ⚠️
📍 MRBIII 1220 ⚠️

Proud to present this pre-print from my lab. Using single-cell multi-omics, 2 mice models, & pt samples, we found CXCR3 as a novel therapeutic target for ICI myocarditis critical for T-cell/macrophage crosstalk and perpetuation of cardiac inflammation biorxiv.org/content/10.110…

Tune in NOW for Breast Cancer Breakthroughs! Hear about the most exciting wins for patients announced at #SABCS23 from Komen grantees. Click here to watch: bit.ly/3X1yPW0

A recent paper from the @balkolab, led by Jamaal James and @bct255, indicates that EZH2 inhibition leads to enhanced MHC-II expression potentially through the improvement of chromatin accessibility at CIITA, the master regulator of MHC-II.

doi.org/10.1136/jitc-2…

Congrats patty spears on such a well deserved award! 2023 Komen Research Advocacy Champion Award! UNC Lineberger #SABCS23 Susan G. Komen 👏👏

Congrats Brandie Taylor!!! Susan G. Komen ASPIRE superstar! So proud

Thursday at #SABCS23 : Examine the role of senescence in breast cancer during a State-of-the-Art Session moderated by Justin Balko, PharmD, PhD. Read a preview in SABCS Meeting News:
bit.ly/482WBHd
BalkoResearchLab #BCSM AACR

Let’s take a closer look at “Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance” by Brandie Taylor BalkoResearchLab at @VUBasicScience Vanderbilt University Medical Center 1/9

Congrats all!!!

Happy to share our work just out at JITC! We highlight the potential of targeting EZH2 as a therapeutic strategy to enhance MHC-II expression and improve immunotherapy efficacy. Jamaal L. James BalkoResearchLab

New #JITC article: Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistance bit.ly/3QS9Bsf Brandie Taylor Catherine Fahey BalkoResearchLab