Delighted to share my first co-first author paper in which we showed the importance of #extendedglycans as functional receptors for recent H3N2 influenza viruses by developing glycoengineered NExt (=N-glycan Extended) cell lines! #glycotime

nature.com/articles/s4146…

Delighted to share the pre-print of a LiGA protocol with detailed instructions to profile the glycan binding preference of cell surface #Siglecs using #ngs #glycotime

Shout out to Mirat Sojitra ednschmidt Guilherme Meira Lima Matthew Macauley Ratmir Derda

biorxiv.org/content/10.110…

Waipan Chan, Ronald Germain et al. NIAID News show that PD-1 engagement by T cells inhibits distinct antigen-evoked signals in a nonlinear manner, strongly influenced by the nature of available TCR ligands. bit.ly/46E19Dk

#TumorImmunology #LymphocyteBiology

That being said, we're hiring at all levels (undergrads, Ph.D. trainees, and postdocs)! Check out our open positions to tackle bioinformatic enzyme discovery, microbial engineering, and cancer immunology at mgriffinlab.com. (Please disseminate widely!)

A viral ADP-ribosyltransferase attaches RNA chains to host proteins | Nature nature.com/articles/s4158…

Can't afford SF rent?

- SF Avg Rent: $3,500/mo
- Vegas Avg Rent: $1,500/mo
- Flight from Vegas to SF: $68

Living in Vegas and commuting to SF 5x a week is $640/mo cheaper than just living in SF.

Thrilled to unveil our research on sialylation in breast cancer! Our data showcases the remarkable power of de-sialylation in transforming immunologically 'cold' breast tumors into 🔥🔥🔥 ones. #Glycotime #BreastCancer
biorxiv.org/content/10.110…

Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux by Stephan H. Spangenberg, Amelia Palermo Briosi, PhD, Gary Siuzdak, Luke L. Lairson, and colleagues at Scripps Research UCLA dlvr.it/Swb3Ht

Our department is hiring a new asst professor! Scripps is a great place to begin your independent career. A truly collaborative environment to address important research questions and world-class resources to pursue scientific problems. Apply to join us! nature.com/naturecareers/…

New work from our group UC Berkeley and collaborators @UCDavis! We used plants as a platform for the production of prebiotic human milk oligosaccharides (HMOs).
Link: biorxiv.org/content/10.110…

Excited for this scripps Chem collaborative work out in nature w/Baran Lab & Lairson Lab. Has a bit of something for everyone…herculean total synthesis, structural reassignment, chemoproteomics, new druggable target, in-depth functional characterization & more

Our latest pre print describing a mechanism for the fast control of clathrin independent endocytosis via glycan remodeling #microscopy #integrin #CancerResearch #breastcancer
biorxiv.org/content/10.110…

Hidey-ho, neighbor!

You know, when working in a lab, we've always found it important to access a variety of online tools. So for #OpenScienceWeek , we updated our blog post listing out said (free) tools!

hubs.la/Q021TrSc0

To all the graduate students at Scripps Research lurking out there on Twitter - we're looking to recruit a student in the immunology program, so if that's you, please email me directly!

Learn more on our website: andersen-lab.com

I am excited to announce that I will be affiliated with a brand new department of Molecular and Cellular Biology at Scripps Research, chaired by Professor Hugh Rosen. AND we are hiring! For more information, see:
apply.interfolio.com/130989

Phage Display of Two Distinct Warheads to Inhibit Challenging Proteins | ACS Chemical Biology pubs.acs.org/doi/10.1021/ac…

Today our preprint on the development of a synthesis tag (SynTag) for chemical protein synthesis came out on ChemRxiv: chemrxiv.org/engage/chemrxi… 🥳

Hartrampf Lab Elyse Williams Aliénor Jeandin UZH Chemistry

“…protein insertases could have a so-far overlooked role in membrane dynamics as scramblases.” #lipidtime biorxiv.org/content/10.110…

I am excited to share that my PhD work on “Epitope base editing CD45 in hematopoietic cells enables universal blood cancer immune therapy” has been published today!

science.org/doi/10.1126/sc…