Qasim et al found that #AKAP12 upregulation in cardiac tissue accelerates #cardiac maladaptive remodeling in animal models, & patients with end-stage #HF have upregulation of AKAP12. Learn more at ahajournals.org/doi/10.1161/CI…

Bradley McConnell @xwehrens

Qasim & colleagues found that AKAP12 upregulation in cardiac tissue accelerates cardiac maladaptive remodeling in animal models, & patients with end-stage heart failure have upregulation of AKAP12. Learn more at ahajournals.org/doi/10.1161/CI…

Arkelius et al found rats treated with #rt -PA after stroke, additional #LOX -1 and #MMP -9 inhibition reduced number & severity of #hemorrhages , & better maintained neurological function compared with rt-PA alone. Learn more at ahajournals.org/doi/10.1161/CI…

Trevor S. Wendt

Hessel & colleagues found that immediate cleavage of #titin springs in otherwise healthy cardiac #sarcomeres alters thick & thin #filament structures related to force production. Learn more at ahajournals.org/doi/10.1161/CI…

@hesselanthony Nichlas M Engels

Check out the latest review in the April 12th issue of Circulation Research by Youn & colleagues on 'The Environmental #Exposome and #AFib : Emerging Evidence and Future Directions' at ahajournals.org/doi/10.1161/CI…

@sadeer_alkindi Emelia J. Benjamin Mina Chung MD Khurram Nasir Zain Ul Abideen Asad, MD, MS, FACC FAHA

Circulation Research April 12th Issue is Out! ahajournals.org/journal/res

Cover: Schematic of the mutant Kir2.1 channel embedded within a lipid bilayer, illustrating the reduced binding capacity of Kir2.1C122Y channel to rainbow-colored PIP2 molecules ;K+ ions-yellow dots.

Ma & colleagues found the pro-atherosclerotic role of #macrophage #Gsα . Learn more about #atherosclerotic prevention & treatment at ahajournals.org/doi/10.1161/CI…

chang ma 山东大学 SHANDONG UNIVERSITY

Padget & colleagues found a direct link of #viral infection to #arrhythmogenic potential before significant host #inflammatory responses and/or myocardial damage. Learn more at ahajournals.org/doi/10.1161/CI…

Rachel Padget Poelzing_Lab @D_RyanKing

Sun et al found #Sorbs2 is transcriptionally regulated by #Nrf2 & decreased in the vessels of diabetic mice. Learn how Sorbs2 deficiency could be an independent risk of coronary #BK channelopathy & #vasculopathy in #diabetes at ahajournals.org/doi/10.1161/CI…

Mayo Clinic

The American Heart Association (AHA) celebrates its 100th anniversary! View the AHA journals Centennial Collection and check back throughout 2024 for a full listing of the articles #AHAJournals #ACC24

ahajournals.org/centennial

Check out the latest review in the March 29th issue of Circulation Research by Fu & colleagues on ' #ECM Interactome in Modulating #Vascular Homeostasis and Remodeling' at ahajournals.org/doi/10.1161/CI…

Kai Wang

Whether you are navigating your first peer reviewer assignment, preparing to submit your first manuscript for publication, or are looking to engage with peers, #AHAJournals have opportunities for you. #ACC24

Find out more today and visit ahajournals.org/early-career

The American Heart Association (AHA) celebrates its 100th anniversary! View the AHA journals Centennial Collection and check back throughout 2024 for a full listing of the articles #AHAJournals #ACC24

ahajournals.org/centennial

Liu & colleagues found #SLIT3 can directly stimulate #cardiomyocyte #hypertrophy via the #ROBO1 receptor. Learn more about this novel cardiac #stromal cell-cardiomyocyte axis which causes adverse remodeling at ahajournals.org/doi/10.1161/CI…

Zhao & colleagues found a novel role of circulatory pro- #CTSD from monocytes in the pathogenesis of #cerebral #microvascular lesions in #diabetes . Learn more at ahajournals.org/doi/10.1161/CI…

Wang & colleagues unravel the vital role of specific #gut bacteria and their metabolites. Learn more about how a high-fiber diet can shape a healthier gut #microbiome which could lower the risk of #T2D at ahajournals.org/doi/10.1161/CI…

Zheng

Check out the latest review in the March 29th issue of Circulation Research by Mesquita & colleagues about 'Biological #Pacemakers : Present and Future' at ahajrnls.org/3UhwQz7

Thassio Mesquita Eugenio Cingolani, MD