A new study by Anvita Singaraju Kathryne Marks Deepak Rao Laura Donlin and colleagues identifies a T cell population as a reason for why some types of immune checkpoint inhibitor immunotherapies can cause arthritis to emerge in some patients.

📄: scim.ag/3wO

#FOCIS 2023 is on its way. Looking forward to an exciting symposium on engineered T-cell therapies as precision treatments for autoimmune diseases and transplant tolerance, co-sponsored by American College of Rheumatology.

Join us on Tuesday, 1:30 PM. Deepak Rao #CART #TCRT #FOCIS

Very excited about this year's American College of Rheumatology symposium at #FOCIS2023 on engineering precision T-cell therapies to treat autoimmune diseases and restore immune tolerance. Deepak Rao Kristi Kuhn, MD, PhD #Immunotherapy #CART

Full schedule online: focis2023.eventscribe.net

Excited to share another Bioinformatician position in our lab based on our recent fundings!! Great opportunity to develop computational AI methods for longitudinal #SingleCell omics for translational medicine! cu.taleo.net/careersection/… CU Department of Biomedical Informatics (DBMI) CU Anschutz Division of Rheumatology DM me directly🙌

So excited to share our #RheumatoidArthritis tissue chromatin atlas of 87K cells from 30 individuals! With, Soumya Raychaudhuri সৌম্য রায়চৌধুরী, Saori Sakaue, Aparna Nathan, Laura Donlin, Kevin Wei and #AMP -RA! NIAMS.
biorxiv.org/content/10.110…
(Tweeting on behalf of the talented Kathryn Weinand)

Excited to share our study investigating pre-existing rheumatoid arthritis (RA) and outcomes after initiation of immune checkpoint inhibitors (ICI) for cancer, led by Dr Kaitlin McCarter

thelancet.com/journals/lanrh…

Happy to share this work on TCRs and BCRs of cells in RA synovium from the AMP RA/SLE Network. Highlights oligoclonal populations, clonal relationships, and more... biorxiv.org/content/10.110… Garrett Dunlap @jenanolikmd Andrew McDavid @[email protected] A. Helena Jonsson Dr. Fan Zhang ⛵️ Soumya Raychaudhuri সৌম্য রায়চৌধুরী

NEW RESEARCH—Patients with pre-existing #rheumatoidarthritis initiating immune checkpoint inhibitors had similar risk of mortality and severe immune-related AEs as matched comparators
thelancet.com/journals/lanrh… Deepak Rao Jeffrey Sparks MD MMSc

Happy to share this report tracking alloreactive T cells in a patient with kidney transplant rejection after anti-PD-1 therapy for melanoma. With Garrett Dunlap, Naoka Murakami, Patrick Ott, Daniel DiToro,
Brigham and Women’s Research
rdcu.be/c744E

Saturday at #ACR22 , @deepakarao will explore the cutting edge of translational research into immune dysregulation in lupus. Read a preview in ACR Convergence Today → acr.tw/3hu5AMp

We have positions open for a flow cytometry sort technician and a core manager at the Center for Cellular Profiling at Brigham and Women's Hospital. Reach out if you want to hear more... ccp.bwh.harvard.edu

Looking forward to seeing many in person at #ACR22 ! Here is a summary of what Brigham and Women's Hospital Rheumatology is currently preparing!

Great paper recently published in ACR_Journals by Deepak Rao Karen Costenbader Jeffrey Sparks MD MMSc and colleagues!

Really important study looking at changes in immune phenotype of early #SLE

Findings show unique T helper cell populations expanded in early disease

onlinelibrary.wiley.com/doi/10.1002/ar…