😮

⚡️With our powers combined, we are Captain #RadOnc ! ⚡️😜

A huge #ESTRO2024 highlight to meet & immediately become besties with inspiring #RadOnc advocates Jeff Ryckman
& Nat Lester-Coll, MD 🙌
Excited to join forces & spread the word that #radiationtherapy cures cancer & saves lives 💫

Fantastic!

👉 highlight the value of what we offer in #radonc

👉 address misconceptions around radiotherapy

Thank you Sandra Turner Lucinda Morris for telling me about this awesome initiative - great meeting you both at #ESTRO24 !

When the transatlantic meet-up turns gourmet! #estro2024
Finally, we met our radoncreview.org wizard Jeff Ryckman and Nat Lester-Coll, MD

#ESTRO24 Piet Ost presenting outcomes of STORM randomized Ph II of MDT v ENRT for oligorecurrent prostate cancer #pcsm

✅ ENRT ⬆️BRFS, LRFS

MDT a/w 8-fold ⬆️ nodal recurrence 3➡️25%

Omitting PB ⬆️ local recurrences 3-fold (5➡️14%), but also increases GU2+ toxicity

#ESTRO24 Dr. David Palma presenting long term results of ORATOR

After 5 yrs fu QOL scores between RT & TORS similar

But trimodality arm a/w ⬇️ MDADI scores

Refutes earlier non-randomized data suggesting ⬆️ outcomes w TORS, due to bias by indication

MultiD evaluation needed!

#ESTRO24 Important negative trial

Sequential chemo-SABR did not improve cancer outcomes, but did increase toxicity vs SABR alone in HNSCC

A few people have asked about the dose escalation strategy. It’s a novel, SABR-inspired approach: heterogeneous dose escalation driven by (but not limited to) the PET volume, *always* respecting OAR - so sometimes part of the PET-GTV only gets 66Gy #radonc #ESTRO24 #medphys

Hanging with the crew at #ESTRO24 !
#radonc

Connor Kinslow, MD

#ESTRO24 Prostate SBRT with empty bladder: challenging the dogma

40 prostate SBRT pts treated with empty bladder (median 81cc)

Similar toxicity to full bladder

BUT short fu though (3 mos)

I love this concept, look forward to long term toxicity results

#radonc #pcsm

#ESTRO24 NARLAL2 ph 3 trial, n=350

With modern RT/QA, dose escalation (mean GTVp 95 Gy, GTVn 74 Gy) improved loco-regional control with no increase in toxicity observed in stage III NSCLC

#radonc #lcsm

#ESTRO24 Flor Verghote adding to the emerging role of adjuvant RT for bladder cancer

Intriguing that only 3/14 pts with positive surgical margins had pelvic failures

#radonc

#ESTRO24 POPART Trial of post op SBRT 32.5 Gy / 5 fx, n=50

Low toxicity reported at median fu ~1 yr, longer fu needed

#ESTRO24 Felipe Couñago PhD presenting HYPORT-ES results

hypofractionated postop RT adjuvant and salvage: 62.5 Gy / 25 fx

96% SRT, 54% received ADT, prophylactic nodal RT not allowed

✅Acute and late gr3+ GU/GI toxicity all <2% with median fu 23 mos
✅ 93% BFFS @ 36 mos

#radonc

Braking radiation, but make it Italian

Bremsstrahlungi

Giulio Francolini: Re-SBRT after previous definitive or salvage radiotherapy (RE-START): A report on the retrospective cohort.

At 302 patients, this is the largest study of which I am aware concerning prostate (70%) or prostate bed (30%) reirradiation!

#AIRO #PCSM #radonc …

Taking a break from #ESTRO24 for afternoon hike

Great to meet Jeff Ryckman at #ESTRO24 !