🎞 superia xtra 400 film sim #btv #vermont

Just Out in the RED journal ASTRO 🇺🇸

The POP-RT trial 🇮🇳found that whole pelvic radiotherapy ☢️for high/very high-risk #ProstateCancer :

➡️resulted in comparable long-term urinary toxicity and quality of life to prostate-only radiotherapy, with no identified significant…

Brendon Stiles My friend Brendon Stiles, you are focusing on the mouse data but not RCTs...

In humans, SABR decreases progression, sometimes increases OS. Even the one negative trial (BR-002) had a HR <1.

BTW still some space in the table any positive surgical trials 😉

A major proportion of recurrences after #prostate -only #RT failed with the caudal most nodal recurrence being 20 mm cranial to the top of pubic-symphysis. 👉implications in defining the caudal border of contouring recommendations. Read here on Journal of Clinical Oncology : doi.org/10.1016/j.clon…

Study out on ASTRO 🇺🇸Advances in #RadOnc ☢️ delves into efficacy & safety of stereotactic radiosurgery for ≥15 brain metastases🧠

✅Revealing favorable outcomes & improved cognition vs. whole brain radiation therapy (WBRT)
✅W/ longer median survival, SRS emerges as a…

well that was cool #Eclipse2024

Durva *after* ChemoRT for LS-SCLC improves OS - look forward to seeing the data!

PORT is alive ... in thymic carcinoma

After R0 resection
👉OS advantage in stages III–IV, 5y 71.6% vs 45.2%

After R1/2 resection
👉 OS advantage especially in stages III-IV, 5y 53% vs 38% p < 0.001
👉 Too small pts numbers with stages I-II
#radonc
jto.org/article/S1556-…

Now European Urology network meta-analysis
👉 ADT+ARPI+RT is superior relative to ADT+ARPI w/ modest ⬆️ in OS in low volume mHSPC.
👉 In de novo low volume mHSPC no significant difference in OS w/ ADT+RT vs ADT+ARPI after adjustment for docetaxel use. europeanurology.com/article/S0302-…

Ahh April in #Vermont

#radonc

Great job done by Wes Kassouf Peter Black
And the McGill University GU team.
⭐Neoadjuvant chemo must be offered before Trimodal Therapy in the management of localized MIBC.

Why is it not adopted in France?
Prof Ananya💙 MathieuRoumiguié Morgan Roupret Evanguelos Xylinas
Thomas Seisen
pubmed.ncbi.nlm.nih.gov/38326142/

Interesting
 
Predictive tools based on activity data may identify patients at risk for unplanned hospitalizations

#AI #radonc #onctwitter JAMA Oncology
ja.ma/4ax3WA1

Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC…
11 years ago we published our findings of no difference. Given more time and more progress, we looked again… Cary Gross Yale COPPER Center

one for the history 📚

bluebird after blizzard 🤘

Breaking from #ELCC (discounting a press release…)

🚨 PACIFIC-2 is negative. No improvement with concurrent and adjuvant Durvalumab with chemo radiotherapy in stage III NSCLC

Jeff Bradley, MD presents at #ELCC 24

Really important data for ILD pts!

Median OS 25 months

10% Gr3 toxicity
7.7% Gr4-5 toxicity (n=3; respiratory deterioration)

Lower toxicity than previously reported - important to consider risks and benefits in this population but SBRT clearly a reasonable option

#radonc

1/ For #KidneyCancerAwareness month The Lancet Oncology has a 50-day full link to TROG Cancer Research FASTRACK II! authors.elsevier.com/a/1ifvZ5EIIgPd…. Thank you Cancer Australia, ANZUP, Varian. A new #radiotherapy standard of care option for inoperable primary #kidneycancer #radonc

Dose constraints used for prostate RT in pts with low metastatic burden M1 dz on STAMPEDE 👇 #radonc #pcsm

Remarkably, the leader behind the UVMMC ransomeware attack was arrested, extradited, and plead guilty

justice.gov/opa/pr/foreign…