Over the next three decades, the global population aged over 65 years is set to more than double.

Are we ready to target the gut microbiome to tackle aging-related inflammation and improve lifespan?

gutmicrobiotaforhealth.com/understanding-…

The role of prebiotics in IBD has been controversial.

FOS and germinated barley foodstuff show potential as effective and safe dietary supplements for induction and maintenance of remission in UC, concludes this systematic review:

academic.oup.com/ibdjournal/adv…

Is it time to speak about a gut–airway #microbiome axis?

Information exchange between these two large mucosal surface areas has implications for the treatment of asthma, chronic obstructive pulmonary disease, and lung cancer Nature Reviews Microbiology:

nature.com/articles/s4157…

Emerging evidence suggests the gut microbiome has much to say regarding diet and nutritional therapies' benefits for IBD.

👉 Follow Nutritional Therapy for IBD for science-based information and tools for your clinical practice.

Antibiotics have negative effects on the gut microbiome.

.Paul Hergenrother & colleagues have developed an antibiotic that kills pathogenic Gram-negative bacteria -even those resistant to other drugs- without impairing the gut microbiome:

nature.com/articles/s4158…

Diet can affect FMT outcomes.

.Haim Leibovitzh et al. showed FMT from diet-conditioned donors followed by the ulcerative exclusion diet led to microbial alterations which correlated with decreased faecal calprotectin via Journal of Crohn's and Colitis:

academic.oup.com/ecco-jcc/advan…

Dysosmobacter welbionis as potential promising next-generation probiotic for improving metabolic health?

gutmicrobiotaforhealth.com/dysosmobacter-…

Do rigorous donor preselection on microbiota level, strict anaerobic processing, and repeated FMT administration matter in ulcerative colitis?

New findings from Severine Vermeire et al. based on the RESTORE-UC trial:

cghjournal.org/article/S1542-…

Is there a role of human milk oligosaccharides for metabolic health?

New findings from Patrice Cani & colleagues in Gut Journal show that the HMO 2’FL influences host metabolism by modulating the mucus layer, gut microbiota and endocannabinoid system:

gut.bmj.com/content/early/…

Why gut microbial β-glucuronidases are relevant?

.The Redinbo Lab et al. found their role in sustaining endobiotic homeostasis and indicate that therapeutic disruptions of this metabolism promote interindividual response variabilities:

sciencedirect.com/science/articl…

Important news for anyone interested in presenting their research findings on #IBS : Take your chance and participate in the international congress IBS DAYS from June 17th - 19th in Bologna, Italy. Register by June 14! Further information: ibsdays.com

How do microbial metabolites shape immune responses?

New findings identify a critical role for butyrate in modulation of myeloid-derived suppressor cells, proposing a novel therapeutic strategy for treating primary biliary cholangitis:

sciencedirect.com/science/articl…

How to advance the emerging field of microbiome-based therapeutics & diagnostics?

Britton, Verdu Lab, Di Rienzi & colleagues update where are and next steps we via American Gastroenterological Association (AGA) Gastroenterology:

sciencedirect.com/science/articl…

Inadequate contamination controls and the absence of culture data and microscopy make it difficult to interpret low-biomass microbial studies.

.Jens Walter & colleagues provide recommendations on how to characterize the microbiome low-biomass samples:

nature.com/articles/s4158…

Modulating the gut microbiota can be an innovative strategy to defend against colonization of antimicrobial-resistant or infectious enteric pathogens.

Why prebiotics and probiotics are worth considering in decolonizing the gut of pathogenic bacteria:

tandfonline.com/doi/full/10.10…

Bacteriocins are potent antimicrobial peptides that are produced by bacteria.

.IvanSugrue, R. Paul Ross & @colinhillucc explore bacteriocin diversity, function, discovery and application as antimicrobials Nature Reviews Microbiology:

nature.com/articles/s4157…

The gut microbiota is closely connected to brain barriers.

.María R. Aburto & John F. Cryan update in Nature Reviews Gastroenterology & Hepatology barrier function across the gut–brain axis:

nature.com/articles/s4157…

Gamma-delta T cells exhibit characteristics of both the adaptive and innate immune systems.

.Tůkką ツ ♔ et al. update the close link between these central immune cells and the microbiome, highlighting potential for immune and brain-related disorders:

mdpi.com/1422-0067/25/3…

It seems that not all microbiome taxa shapes Alzheimer's disease risk on the same way.

.Laurie Cox et al. identify immune mechanisms by which specific bacteria can contribute to disease pathogenesis:

nature.com/articles/s4146…

Engineered microbe-based therapeutics for IBD?

Preliminary findings found targeted delivery of Saccharomyces boulardii to the extracellular matrix enhanced recovery in murine colitis:

nature.com/articles/s4146…