A cross-disciplinary research team from CUHK Engineering & CUHK Medicine develops retrievable nanorobots for targeted and enhanced thrombolysis, potentially saving stroke patients from brain damage. Published in #ScienceAdvances #ScienceRobotics . Details: bit.ly/3VIovFE

New non-randomized comparidon of andexanet alfa and usual care (i.e. PCC and/or TXA) in patients with factorXa-inhibitor- ICH - high rate of continuous bleeding (aka haematoma expansion) with usual care. Andexanet was associated with lower incidence of HE Stroke Research Center Bern Bernhard Siepen

Bonaventure Ip et al. provide overview of the pathophysiology of vascular cognitive impairment, and outline how an understanding of underlying mechanisms may inform the development of novel therapies. Ho Ko Bonnie Lam Vincent Mok CUHK Neurology

ahajournals.org/doi/10.1161/ST…

CU Medicine & UCL🤝🏻Prof Anthony Smith, Vice-Provost of @UCL, visited CUHK Medicine to exchange in learning opportunities and #research collaboration on 21 March.

The April issue of #Stroke is now available. Check out the issue for the latest Clinical Trials and Original Contributions, as well as a Focused Update on vascular cognitive impairment and dementia, Topical Reviews, Special Reports, and more. #AHAJournals ahajrnls.org/3PCkzCt

Current and Future Treatments of Vascular Cognitive Impairment | Stroke ahajournals.org/doi/10.1161/ST…
A review on treatments of VCI by our team!

Now we need to improve secondary prevention strategies for vulnerable patient groups like those with a history of ICH #ENRICH -AF PHRI.ca Population Health Research Institute 🇨🇦 and those with #breakthroughstrokes despite anticoagulation with our Schweizerischer Nationalfonds (SNF) funded ELAPSE Urs Martin Fischer Lorenz Räber, MD PhD

In a Review, David Seiffge and colleagues provide an update on secondary stroke prevention in people with atrial fibrillation: thelancet.com/journals/laneu…
@strokebern
@ash_shoamanesh
@fishingNeurons
Valeria Castro
@UCLstrokeRes
@raberLorenz

Statin use in stroke patients with CMBs?
Likely rather beneficial than harmful, even in those with multiple CMBs! #microbleeds Neurology Journal
neurology.org/doi/10.1212/WN…

Neurological complications of modern radiotherapy for head and neck ca... sciencedirect.com/science/articl…

Interested in learning more regarding predictors of hematoma expansion and response to andexanet alfa in patients with FXaI-associated ICH participating in the ANNEXa-I trial?
I summarize our findings with NeurologyLive here:
neurologylive.com/view/secondary…
#neurotwitter McMaster University Department of Medicine

Tracking and navigation of a microswarm under laser speckle contrast imaging for targeted delivery | Science Robotics science.org/doi/10.1126/sc…
Proud to be part of our work in tracking the nanorobot behavior by LSCI in endovascular models. Ho Ko CUHK Neurology

Professor Richard Kay Li-chi, a world-renowned expert on neurology and former Chief of Neurology at the Department of Medicine and Therapeutics at CUHK, passed away on 15 February 2024. CUHK Neurology is deeply saddened over his passing and he will be remembered fondly.

Happy to share our study showing that APOE e4 is a risk factor for ICH in pts with brain AVMs.

- Odds ratio of 4 > promising role in prediction
- CAA is the mediating mechanism?

Thank you Daniela Renedo for your leadership.

Please take a look! shorturl.at/azS08

Via #ISC24 : #COVID19 vaccination does not worsen imaging markers of #CerebrovascularDisease : bit.ly/4bCmvUF

#NeuroTwitter #coronavirus @AANMember AHA Science CUHK Neurology Upstate Medical University

This retrospective study suggests that changing pre-stroke DOAC does not reduce recurrent cerebral ischemia in patients with #AtrialFibrillation who develop ischemic stroke on DOAC therapy. #AHAJournals ahajrnls.org/3UIDBKM

Intracerebral haemorrhage in patients taking different types of oral anticoagulants: a pooled individual patient data analysis from two national stroke registries
svn.bmj.com/content/early/…

No better life than a life spent laboring at love -Congratulations Shadi Yaghi on completing this passion project: STOP-CAD examining an 4K pts w cervical artery dissection.
AP similar to AC for preventing recurrent stroke.

#ISC24 is a wrap!

Spectrum of OAC-ICH changed dramatically, FXaI now the majority. Poor outcomes with current reversal, need better treatments. Great Norwegian-Swiss collaboration Stroke Research Center Bern Bernhard Siepen Espen Saxhaug Kristoffersen Johannes Kaesmacher Thomas Meinel Urs Martin Fischer Martina Göldlin

svn.bmj.com/content/early/…

Principles for blood pressure titration in the acute phase of ICH #ISC2024 Craig Anderson presents his groundbreaking work in ICH and blood pressure lowering in the acute phase. Excessively high blood pressure could lead to hematoma expansion.