Many males aged 70 years and older or those with a high risk of death within 10 years undergo prostate cancer screening despite the recommendation against screening in these populations by current guidelines, finds cross-sectional study. ja.ma/44k0Tcr

A publicly funded IVF program mandating an elective single-embryo transfer policy was associated with a reduction in multifetal pregnancy rates, finds this study of more than 1.7 million pregnancies in Ontario, Canada. ja.ma/4aV9Rzp

Nationally representative cross-sectional study observed that psychiatric symptoms are more common in people with post-COVID condition than in other US adults, but many do not receive mental health treatment. ja.ma/4aPXKDF

Prolonged deployment to military bases with open burn pits was associated with increased risk of developing asthma, COPD, and hypertension. ja.ma/4aKZVIG

Mandatory DMV policies for clinicians to report patients with dementia may be associated with a higher risk of missed or delayed dementia diagnoses, finds cross-sectional study of primary care clinicians. ja.ma/3xOOEIW

Patients who were hospitalized with severe COVID-19 and achieved higher projected abatacept exposure had reduced mortality and a higher probability of recovery with fewer safety events. ja.ma/3y07T1X

A letter intervention targeting high-volume PCP prescribers of the antipsychotic quetiapine reduced receipt of this medication among their patients with dementia without detectable adverse health impacts. ja.ma/4drEHl5

This cross-sectional study found that, during clinic days with both telemedicine and in-person visits, PCPs had 5.6% to 6.2% more EHR-based work. ja.ma/3xIxa0z

Multimorbidity and poor self-reported health and quality of life were associated with a higher risk of subsequent fracture and mortality in fracture patients, underscoring the importance of managing fracture patients with multiple conditions. ja.ma/3U5HEyI

The associations between neighborhood-level socioeconomic deprivation and facility-level inappropriate antipsychotic medication use in nursing homes were strongest in nursing homes with the lowest staffing levels. ja.ma/3JxJEe9

Study finds that IUD use increased in South Carolina during the Choose Well Contraceptive Access Initiative when compared to a peer state. ja.ma/3JSP0B7

Study shows flu ICD-10 codes are highly specific and moderately sensitive. Flu codes likely represent true positive cases of flu. Studies using ICD codes may accurately identify flu cases but will likely miss some cases. CDC Flu @VUMCHealth ja.ma/3Ubhevn

This cohort study examines prespecified health outcomes after vaccination with an ancestral monovalent COVID-19 vaccine in US children aged 6 months to 17 years. ja.ma/3xIxe0j

Randomized clinical trial found an effect of expectations regarding the role of a patient with respect to clinical and study outcomes. ja.ma/4bs50Wv

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What is the cost-effectiveness viability of semaglutide compared with endoscopic sleeve gastroplasty over 5 years for individuals with class II obesity?

ja.ma/4aCQH1e

In confirmed SARS-CoV-2-naïve individuals from early trials, modest increases in specific saliva IgA are detected after mRNA vaccination using ultra-sensitive digital ELISA, but robust mucosal responses are only observed in previously infected individuals. ja.ma/3xHM33e

Prescribing of psychotropic medication for children and adolescents in France significantly and persistently increased after the onset of the COVID-19 pandemic, finds cross-sectional study using time-series analysis. ja.ma/4b420zd

Case analysis of >3.9 mil COVID cases in California found that pediatric vaccination averted >375,000 cases of COVID-19 and 270 hospitalizations in children 6mo-15yrs in the 4 to 7 months following vaccine availability. Jennifer Head-Zhutenegger Justin Remais ja.ma/3JuSQjp

In this pan-Canadian cohort study of postpartum individuals, those with severe maternal morbidity had 26% higher risk of a future mental health hospitalization or emergency department visit in the following 13 years compared to those with no morbidity. ja.ma/4dlenJg

Individuals with persistent favorable sleep patterns over 5 years had a lower CVD risk, even among those with higher genetic risk. These findings highlight the importance of maintaining favorable sleep patterns over time for CVD prevention. ja.ma/4b5ekzh