📣📣Introducing 'Au Contraire' section of JACC Journals #JACCHF
Share unconventional ideas, challenge accepted wisdom, & present alternative perspectives in #HF

BiykemBozkurt Eiran Gorodeski, MD, MPH Novi Tham Nikhil Narang, MD Viviana Navas, MD Jenny Thibodeau, MD, MSCS Tariq Ahmad MD MPH
👉 jaccsubmit-heartfailure.org/html/au-contra…

An analysis of The Donor Heart Study teaches us that #ECG abnormalities are extremely common in brain dead organ donors, are largely reversible on serial #ECG testing, and are not correlated with post- #HeartTransplant graft survival.

shorturl.at/lVX13

#AF ib can impair ventricular function over time in up to 50% of patients
#AF -induced #cardiomyopathy mechanisms include systemic inflammation, oxidative and metabolic stress, cardiomyocyte calcium mishandling, and structural remodeling

More in JACC HF: shorturl.at/rtDU3

New work in JACC Journals #JACCHF on the treatment effects of ICDs for patients with chronic HFrEF—baseline frailty status significantly modifies risk of all-cause mortality in this large cohort from SCD-HeFT Matt Segar Neil Keshvani ambarish

📎 tinyurl.com/57z4fhfy

#JACCHF JACC Journals reports quad therapy with ARNI, BB, MRA, & SGLT2i ⬇️ risk of CV death & HHF in HFmrEF & HFpEF.
-Driven by ARNI, MRA, SGLT2i.
-More pronounced in HFmrEF.

♦️Is it time for #GDMT for all HF?♦️

👀: jacc.org/doi/10.1016/j.…
Editorial: jacc.org/doi/10.1016/j.…

It is sometimes the bravest and strongest thing to say “no” and prioritize other aspects of life. Even if it’s an incredible opportunity. Even if it’s an honor to be asked to do something. I’m sure more than one person could hear this today! It’s okay to say no! 💚💪🏼👑

Is #Mavacamten beneficial for #OHCM with HTN❓

✔️Equally effective for symptomatic #OHCM with/without HTN
✔️ Similar improvement on LVOT gradient, NYHA FC, peak VO2, QOL, NTproBNP, &echocardiography

Read more🖇️: jacc.org/doi/10.1016/j.… #JACCHF #EXPLORERHCM

New in JACC HF:

The OCS Heart EXPAND Trial

Expanded criteria DBD hearts were preserved with #TransMedics OCS

High utilization of donor hearts with good 30-day survival without PGD

Do these outcomes resemble your clinical practice?
shorturl.at/cfksA

#HeartTransplant

In the latest issue of JACC Journals #JACCHF , data from GUIDE-IT demonstrate repeated NTproBNP measurements in HFrEF predict outcomes & support their use in guiding clinical decision making. @michaelfuery Tariq Ahmad MD MPH James Januzzi Jr MD

➡️jacc.org/doi/10.1016/j.…

🏷️ Use of OCS to perfuse, optimize ECD🫀 with DBD —> ⬆️ utilization for OHT 👌post-OHT clinical outcomes.

🏷️ OCS ⬇️ ischemic injury

👉 jacc.org/doi/10.1016/j.…

JACC Journals #JACCHF
Jacob Niall Schroder Adam DeVore, MD, MHS Kenneth Liao, MD, PhD Scott Silvestry MD Donna Mancini Jason W. Smith, MD. FACS.

🏷️ #HF complex syndrome categorized by LVEF.
🏷️ #LVEF is prognostic for AEs & predicts response to 💊
🏷️ Simple LVEF terms may ⬆️ #GDMT utilization
🏷️ individualized dx-t/t paradigms needed for #HF pEF
JACC Journals #JACCHF HF Collaboratory

New in JACC HF:

Metabolic Vulnerability Index: a new inflammatory and metabolic score associated with mortality risk in Heart Failure

shorturl.at/hAJKS

US cohort of 63,759 patients with new #HFrEF

Triple #GDMT used in only 6.2% of patients at 12 months!!!

🆘🆘🆘🆘

😱 Lack of urgency
😱 Go slow
😱 Drawn out sequencing
😱 Therapeutic inertia

Is a highly ☠️ combination

Please start quadruple GDMT now

doi.org/10.1161/circul…

In recognition of heart failure awareness week, Jenny Thibodeau, MD, MSCS shares insights on getting heart failure patients the medications they need. Learn more about the 'fantastic four' medications that are recommended for heart failure with reduced ejection fraction: bit.ly/3UAbRaP

Shared during Cardiology Grand Rounds today. Amazing how many strong, intelligent, super women are part of #utsw cardiology. Too many fabulous colleagues to tag! Women as One UTSW Heart

Poor sleep was associated with an immediately heightened risk for self-reported AF episodes, and a dose-response relationship existed such that progressively worse sleep was associated with longer episodes of AF the next day. bit.ly/3HPDHIQ

#JACCCEP #AFib #EPeeps