1/17
Thrilled to announce our Gastroenterology paper, where we tackle the challenging exocrine #pancreas context to achieve unprecedented scRNA-seq definition of cell landscapes in homeostasis, #AcutePancreatitis , and recovery. Led by NissimLab @aneykatie + Woo-Jeong Jeong. 🧵👇

It's out! We report 3D mapping of human pancreatic precancer and associated genetic alterations. With the brilliant Ashley Kiemen and Denis Wirtz . Tweetorial to follow soon. nature.com/articles/s4158…

Come join our group! Please share with those interested.

careers.dana-farber.org/job/scientist-…

Very interesting paper that makes me think differently about how monoallelic loss of #BRCA2 can lead to #PancreaticCancer .

cell.com/cell/fulltext/…

Incredible progress!

Really enjoyed my first Cholangiocarcinoma Foundation Meeting. Wonderful meeting for learning and collaboration. Cholangiocarcinoma Foundation

Team science is clearly the future but figuring out how to get there is hard. In this inspiring article, Jesse Boehm and Tyler Jacks discuss best practices for successful collaborations. Beautifully written with many historical and current examples.

aacrjournals.org/cancerdiscover…

Loved 'Rough Sleepers', an inspiring #book about a team of healthcare workers devoted to caring for the #homeless . Incredibly challenging work. The book's message is that no matter who you are taking care of, medicine is always about relationships. Boston Health Care for the Homeless Program
a.co/d/86jIqBV

Cancer affects everyone.
As the Princess bravely said: 'Do not lose faith or hope. You are not alone.'
Wishing faith, hope, and a speedy recovery, to her, the King, and all others facing cancer.

It was a privilege to present the exploratory analyses of #HPV circulating DNA Naveris, Inc. in our Dana-Farber trial studying pembrolizumab in anal cancer at #EUROGIN2024 !

Excitingly, the results were published in Journal for ImmunoTherapy of Cancer: jitc.bmj.com/content/12/1/e…


James Cleary EUROGIN Conference

A collaborative effort to engineer a dual knock-in reporter system to simultaneously broadcast aberrant stem cell and differentiation activity in colorectal cancer for discovery science. Jun Qi Lab Pornlada Likasitwatanakul Paul Doan Zhixin Li, PhD
nature.com/articles/s4146…

Congratulations Ann! Stanford is getting a wonderful hematologist and physician scientist who I’m sure will do extraordinary things leading their hematology department. We will miss Ann enormously.

Remembering Dr. Howard Hiatt, a PIH mentor and global health champion 🕊️

Dr. Hiatt passed away on March 2. Well-known and respected in the public health field, Dr. Hiatt played pivotal roles in his decades-long involvement with PIH.

Read more: bit.ly/3T1RUHD

How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s4158… Bo Xia

Very happy for Einstein! I loved my time in the Bronx. Its a great place to learn medicine.

$1 Billion Donation Will Provide Free Tuition at a Bronx Medical School nytimes.com/2024/02/26/nyr…

Surprising result! A thyroid hormone receptor β (THR-β) agonist appears effective in improving #NASH .

Decreased THR-β activation promotes NASH by 'reducing mitochondrial function and β-oxidation of fatty acids' which ultimately leads to fibrosis.

nejm.org/doi/full/10.10…