Helping put together⭐️Embracing #cancer complexity: Hallmarks of systemic disease⭐️in Cell was a unique experience! Honored to participate in mapping out the complexities of cancer as a systemic disease🎯.🙏Charles Swanton and all coauthors really for this endeavour!

Embracing cancer complexity: Hallmarks of systemic disease Charles Swanton Elsa Bernard Auwerx Lab Susan Bullman Catherine Elliott Ayelet Erez Gerard Evan Febbraio Laboratory Andrés Hidalgo Mariam Jamal-Hanjani Johanna Joyce Lab Matt Kaiser Katja Lamia (she/her) Jason Locasale Sherene Loi, MD Miriam Merad, MD, PhD Jennifer Wargo MD

#OpenAccess in Cancer Discovery Radical Collaboration: Reimagining Cancer Team Science From Break Through Cancer’s Jesse Boehm and Jacks Lab aacrjournals.org/cancerdiscover… Figure below: “The Hallmarks of Cancer Collaboration”

Somatic Mutations in Normal Tissues: Calm before the Storm By Humam Kadara Paul Scheet 🌮🧬 Zahraa Rahal MD Anderson Cancer Center aacrjournals.org/cancerdiscover…

"populations with a high prevalence of aging, chronically diseased, and socially disadvantaged people are particularly susceptible to air pollution–associated disease"

What is the role of the TME in lung cancer evolution? We are excited to share our new TRACERx paper “Spatial Architecture of Myeloid and T Cells Orchestrates Immune Evasion and Clinical Outcome in Lung Cancer” at #AACR24, out in Cancer Discovery today rb.gy/q484j9 Tweetorial👇

"Survivors of cancer aged 5% faster per year ... Biologically, older and faster-aging survivors ... had a higher risk of frailty and died earlier than those with slower biological aging, suggesting a potential opportunity to intervene on excess aging." nature.com/articles/d4158…

44 years after Terry embarked on his #MarathonOfHope, his dream lives on through the work of the patients, researchers, oncologists, lab technicians, donors and hospital administrators that make up the @MarathonOfHope network. Thank you all. Terry Fox Research Institute TerryFoxFoundation

Out now! Our Nature Medicine paper discussing the importance of understanding cellular and molecular mechanisms of damage in climate-related health outcomes to best plan interventions that mitigate harm: nature.com/articles/s4159…

This study challenges the idea that cancer is caused only by permanent changes to DNA go.nature.com/3Wfy4fb

And thanks to the brilliant Cancer Grand Challenges team at CRUK for their total support since Mutographs started, as well as wonderful scientific journey with Wellcome Sanger Institute and UC San Diego colleagues (esp Sarah Moody), partners in the 11 countries, and all the great team IARC.

Why do some patients benefit less than others from precision cancer medicine? We are excited to share our paper "Mixed responses to targeted therapy driven by chromosomal instability through p53 dysfunction and genome doubling” out in Nature Communications. nature.com/articles/s4146… 🧵

The Edwin S.H. Leong Centre for Healthy Aging is now accepting applications for the UBC Healthy Aging Postdoctoral Fellowship. This fellowship provides $60,000 funding for 1 year with the possibility of a 1 year renewal. Please see: healthyaging.med.ubc.ca/funding-opport… for more information

Two ways that environmental factors can alter somatic mutational landscapes

“#HealthyAging is inextricably linked to the health of our planet.” Hear from Dr. Michael Kobor and Dr. Kim Schmidt on how the natural environment and aging are connected, and what you can do to safeguard your health in a changing climate. ➡️ bit.ly/4eR0qTT Edwin S.H. Leong Centre for Healthy Aging

New paper from MD/PhD student Peiyao in the lab investigating the unique features within lung cancer patients who formerly smoked and how this impacts tumor biology and clinical outcomes: …nslational-medicine.biomedcentral.com/articles/10.11…

⭐: Dr. Emilia Lim Emilia Lim, University of British Columbia University of British Columbia 📝: Investigating the associations between ambient air pollution exposure and genomics, epigenomics and metabolomics 🔗: ow.ly/sVct50SzAip

📢The Department of CPS UBC Cellular & Physiological Sciences, in collaboration with Edwin S.H. Leong Centre for Healthy Aging and UBC Life Sciences Institute, invites applications for a tenure-track Assistant Professor position! Apply by Sept 21, 2024 ubc.wd10.myworkdayjobs.com/ubcfacultyjobs…

A new study suggests that #Parkinson's disease originates in the gut. washingtonpost.com/wellness/2024/… That takes us back again to Braak's hypothesis from 2 decades ago. It's orchestrated, not an either or, as portrayed here. science.org/doi/10.1126/sc…