As a #disease #mechanism , cytosolic #DNA accumulation is way more prevalent than we appreciate. Alice Rannou gave us a #primer on how to measure it in #macrophages … very helpful.
Smidt Heart Institute at Cedars-Sinai

Fascinating #labmeeting by Thassio Mesquita on #fibrosis in #HFpEF . Targeting FOXO1 in #fibroblasts improves #diastole and reduces #VT #inducibility in 2-hit mice. Smidt Heart Institute at Cedars-Sinai Cedars-Sinai Academic Medicine

Starting Chapter 2 of @cedarssinai @caltech joint symposium… looking forward to awesome discussions!

Giant #sequoias are the largest organisms on Earth (for scale, look for a human adult by the tree on the right) and among the oldest. Their shallow roots, thirst and thick bark make for a narrow comfort zone, 5-8k ft in elevation on the western slope of the Sierra Nevada. We are…

Proud of your great work, Zahra Mohammadi Goldar, MD, which offers new hope for extending #transplant #graft #survival using our novel #RNAdrugs .
Cedars-Sinai
Smidt Heart Institute at Cedars-Sinai

Today’s #journalclub was immuno-centric: FANCI, LIPSTIC, #RNA damage. Lots of great didactics from Jianyi Yu of Tsinghua University medical school, Alessandra Ciullo and Peter Heeger, #immunologist extraordinaire. This stuff is as complex as #electrophysiology ! 😵‍💫😳🤣
Smidt Heart Institute at Cedars-Sinai…

More lovely data, this time from Alessandra Ciullo and Ahmed Ibrahim, Ph.D., MPH:
Smidt Heart Institute at Cedars-Sinai
#RNAdrugs

Data review with Thassio Mesquita and Eugenio Cingolani, MD. Sometimes the #data are compelling not only in their quality, but also in their beauty!
Smidt Heart Institute at Cedars-Sinai
Cedars-Sinai Academic Medicine
#EPeeps

First time blood donor! Honored to serve our patients.
Smidt Heart Institute at Cedars-Sinai
Cedars-Sinai

Bravo Dr. Michael Farkouh !!
Smidt Heart Institute at Cedars-Sinai

Today’s inaugural Caltech-Cedars-Sinai symposium on #stemcells and developmental biology was a great success. Such stellar science! 🙏 Ophir Klein, marianne bronner, Magdalena Zernicka-Goetz and Jeffrey Golden for organizing.
Smidt Heart Institute at Cedars-Sinai
Cedars-SinaiMed

Bang-up Eduardo Marban, MD, PhD mtg presentation by NIH NHLBI #T32 fellow Xaviar Michael Jones gives new hope for #scleroderma . In two #mouse models and human #SSc #macrophages (🙏Francesco Boin MD), #ncRNA drug TY1 attenuates #DNAdamage and reverses disease. 👍. Thanks Mike for your great work!…

Practice talks for AATS reveal great #diversity of themes and presenters from Smidt Heart Institute at Cedars-Sinai dept of cardiac surgery headed by Jo Chikwe
Cedars-Sinai Academic Medicine

Super bonito!