Thrilled to share our work profiling Ale yeast protein dynamics across fermentation and serial repitching! biorxiv.org/content/10.110… Maitreya Dunham Edward Marcotte Live Oak Brewing Co. #BeerYeast #SystemsBiology #Proteomics Sneek Peak thread🧵 below

Super fun project with Riddhiman Garge, Edward Marcotte, Live Oak Brewing Co., and friends! Systematic Profiling of Ale Yeast Protein Dynamics across Fermentation and Repitching biorxiv.org/content/10.110…

We are happy to present our workflow DQGlyco enabling the in-depth quantification of glycoproteome dynamics. In total, we characterize > 150,000 glycoforms in the mouse brain. tinyurl.com/DQGlyco

Out now in eLife - the journal: We explore how genetics and environment rewire muscle insulin signalling

Featured here: elifesciences.org/for-the-press/…

Available here: elifesciences.org/reviewed-prepr…

A thread

How many different protein shapes are there in 200 million predicted AlphaFold structures? In a joint project with Martin Steinegger 🇺🇦 we (@ibarrioh, Jingi Yeo
et al) clustered these into around 2 million groups to study their novelty and evolution nature.com/articles/s4158…

I am truly excited to share one of the major works to emerge from my postdoc, now on bioRxiv:
biorxiv.org/content/10.110…

We explore the role of differential 'substrate quality' on the phosphorylation of kinase targets, using as our case study the master kinase CK2 (1/n).

We are looking for a #PhD candidate! Are you interested in #chromatin and want to combine high-throughput methods & molecular biology to understand how histone #PTMs regulate chromatin functions using #yeast ? 👩‍🔬🧑‍🔬🧫🧬 Contact us 👇Please spread the word!

Excited to attend #ASMS2023 and present our approach to study cellular aging using multidimensional proteomics:

The method might be cheap, but the data is priceless.

Our Yeast 5k Proteome Project is now published in Cell.

We measured proteome profiles for almost 5,000 single knock-out yeast strains. We show what drives protein changes and how this resource can be used for functional annotation of genes and proteins.
cell.com/cell/fulltext/…

Do you want to see how #AlphaFold2 can be applied to study protein-protein interactions? Join us for a new #FGCZseminar where Pedro Beltrao will show its potential and limitations.
April 25th, 16:00-17:00
Registration required
Apero will follow
#proteomics , #interactionproteomics

#prolfqua - happy to share doi.org/10.1021/acs.jp… as #openaccess Journal of Proteome Research article by my colleague Witek W 🇺🇦 FGCZ Thank you, editor Magnus Palmblad (@[email protected]) and reviewers, for your work. source code: github.com/fgcz/prolfqua #RStats #proteomics #massspectrometry