Xiaoxiao Ma
@Pheno2geno
USTC-COH-MSKCC-CCF
Postdoc working on immunogenomics and immunotherapy to fight against cancer with Timothy Chan.
Tweet my own opinion.
15-01-2019 21:00:44
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We applied mutational signature based-models to identify patients with functional POLE/D1 mutations. Up to 75% of these patients benefited from immunotherapy in our cohort. The mutation processes shape the biochemical landscape of neoantigens. Check out more Nature Genetics πππ