Are oligonucleotides that are chemically optimized for normal brain also active in glioblastoma brain tumors? 👇 Hassan Fakih, Ph.D. Jon Watts

In the latest paper from senior PhD student Samantha Sarli, we compare the activity profile of conjugated and unconjugated ASO and siRNA conjugates in glioblastoma xenograft tumors in vivo. Amphiphilic lipids help drive safe uptake! Online now at NAR: academic.oup.com/nar/article/do…

Thankful to RNA Therapeutics Institute for support to bring 5 Mount Holyoke College undergrads to #RNATx2024 ! Excited for them to share their #UndergradResearch and to hear talks from amazing scientists Doudna Lab, Sonia Vallabh Eric Vallabh Minikel, Tracy Johnson, Blanton Tolbert and more! So stoked - yay RNA!🧬💜🧬

Poster Abstract Deadline for #RNATx2024 today! Can’t wait to see what you’ve been working on!

Love our monthly RTI chalk talks! Today is the Watts’ lab Jon Watts turn with Sam Sarli, Adam Hedger, & Krishna Ghanta 🍕🧬

This paper has moved on to Round 3 of the bracket-style competition STAT Madness, assembled by STAT News. Voting closes on Thursday, March 21, at 11:59 p.m. Click on the UMass Chan logo to vote.
statnews.com/feature/stat-m…

The Anderson lab and Wen Xue identified an ideal lipid nanoparticle to deliver mRNA and CRISPR components into lung tissue. Published in Nature Biotechnology, the research demonstrated that we could effectively edit genes in the lung airway epithelial cells.

Fresh off the press! Modular vector assembly enables rapid assessment of emerging CRISPR technologies pubmed.ncbi.nlm.nih.gov/38484704/ ErikSontheimerLab

Less than ONE WEEK to submit your abstract for a poster presentation at our sixth annual RNA Therapeutics: From Concept to Clinic symposium. umassmed.edu/RNATx/abstract…

The Wen Xue's paper is the last one standing from UMass, so please help our colleagues continue on to the Elite Eight by voting again; five days left of voting! Click on the link below, sign in, look for UMass Chan icons, and VOTE! statnews.com/feature/stat-m…

A huge thank you to the talented individuals who made these delicious pies! 🙌 RTI's finest indulged in the slice of success at Athma Pai's Pai Day! 🥧✨ Thanks to everyone who joined us and made it a pi-fect party! #PiDay #RTI

In collaboration with SACNAS, ScienceLIVE explored organ systems with the young women in the Eureka! program at Girls Inc. of Worcester #UMassChan
T.H. Chan School of Medicine at UMass Chan
Morningside Graduate School of Biomedical Sciences
@sacnas

Nobel Prize winner to deliver address at UAMS Student Research Day katv.com/news/local/nob…

Fresh off the press: Endogenous trans-translation structure visualizes the decoding of the first tmRNA alanine codon Korostelev Lab

frontiersin.org/journals/micro…

Have you submitted your abstract to #RNATx2024 yet? TODAY is the last day to submit your abstract for a short talk at the 2024 RNA Therapeutics: From Concept to Clinic (in person and virtual!) RT & share with colleagues! go.umassmed.edu/abstracts

Have you submitted your abstract to #RNATx2024 yet? Less than ONE DAY left to submit your abstract for a short talk at the 2024 RNA Therapeutics: From Concept to Clinic (in person and virtual!) RT & share with colleagues! go.umassmed.edu/abstracts

Hot off the press: EZH2 inhibition reactivates epigenetically silenced FMR1 and normalizes molecular and electrophysiological abnormalities in fragile X syndrome neurons Jon Watts

Read more: pubmed.ncbi.nlm.nih.gov/38449737/

Watts lab research was selected to compete in STAT Madness again this year! This time the featured research is our collaboration with Joel Richter's lab, building on their key insight that splice-switching ASOs may be therapeutic for Fragile X. Vote here: statnews.com/feature/stat-m…