Excited to share our latest work on Toxoplasma serotyping. We describe the potential of GRA peptides to discriminate type II and III infections in sheep🐑 and pigs 🐖, two of the most relevant hosts for toxoplasmosis epidemiology. Check it out here 👇
doi.org/10.3389/fcimb.…

Just updated!

We updated our massive database of funding opportunities for POSTDOC fellowships.

Each entry (316!), we provide the $ amount, deadline, eligibility criteria, description, and link to funder.

Download this database freely here: research.jhu.edu/rdt/funding-op…

Excited to share our new story explaining how macrophages use nitric oxide derivatives to shut down Toxoplasma evasion of cell-autonomous immunity. Congrats to Xiaoyu Zhao and the team! link.springer.com/10.1038/s41467…

New findings in Toxoplasma gondii research: GRA72 and GRA47 identified as pore-forming proteins on PVM, critical for nutrient flux and parasite virulence. This discovery opens avenues for novel therapeutic interventions. Mebratu Bitew SaeijlabUCdavis #mBio journals.asm.org/doi/10.1128/mb…

Excited to share my latest paper out in mBio . This is a great collaborative work between SaeijlabUCdavis , Prof. Jorge E. Contreras and Christopher Swale. This work cannot be done without excellent collaborations.

journals.asm.org/doi/10.1128/mb…

Our paper on ITCH-mediated NLRP1 inflammasome activation during Toxoplasma infection is finally published online: journals.asm.org/doi/10.1128/mb…
This is a great teamwork. Many thanks to members of SaeijlabUCdavis and our collaborators Prof. Hao Wu Bobby Hollingsworth Bennett Penn.

The GRA conspiracy's takeover of #Toxoplasma destiny ! With Antonio Barragan steering the ship and SaeijlabUCdavis on board, we're rewriting the (chromatin) rules of parasite dissemination.

biorxiv.org/content/10.110…

🚨 European Multicolloquium of Parasitology (EMOP) 2024 (European Multicolloquium of Parasitology - EMOP) 🚨

- Held every 4 years & hosted in 2024 by the Polish Parasitological Society in Wrocław!
- August 26-30th 2024
- Registration & abstract submission at bitly.ws/3atvN
-More at eurofedpar.eu

I am delighted to share my last postdoctoral work SaeijlabUCdavis, where we found host E3 ubiquitin ligase ITCH mediates NLRP1 inflammasome activation after Toxoplasma gondii infection in rat macrophages and IFNgamma-induced anti-Toxoplasma responses in human cells.

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous ... biorxiv.org/cgi/content/sh… #biorxiv_immuno

50 years after the discovery of the #Toxoplasma life cycle by Frenkel et al. we have reached a milestone by producing pre-gametes in vitro - a feat previously only possible by infecting cats. Exciting details in our latest nature study. Thread below🧵1/8

nature.com/articles/s4158…

GRA47 and GRA72 are Toxoplasma gondii pore-forming proteins that influence small molecule permeability of the parasitophorous vacuole biorxiv.org/cgi/content/sh… #biorxiv_micrbio

Kirk Jensen Dan Gold Deeply saddened by Dan's Dan Gold passing. His pivotal role in biochemistry at the Saeij lab, from MIT to Davis, was immense. His mentorship, critical thinking, and guidance shaped our lab's success. His vibrant personality will be profoundly missed.

Please RT:
Applications are open at tinyurl.com/applyBoP for the 2024 Biology of Parasitism course BiologyofParasitism Marine Biological Laboratory (MBL) with new deadline: January 3rd !!
Come join us for an amazing summer of learning and camaraderie, exciting lectures, lab practicals and fun excursions.

Writing is an absolutely critical skill… and one that can be improved dramatically. Doing so requires not just repetitions, but deliberate efforts to improve. Some tips here: docs.google.com/document/d/1jB…

Are you a #DVM interested in a research career? Check out the Comparative Medical Scientist Training Program UC Davis Veterinary Medicine! Choose from 8 programs including Graduate Group Integrative Pathobiology ! Want to know more about this #PhD program, register for the virtual town hall: ucdavis.zoom.us/meeting/regist…

Tweetorial of the PIM1-GBP1 guard mechanism by the amazing Daniel Fisch below. I finished this for my son Leo, we all have him in our hearts. 💚 Thanks to all authors for making it happen; read to the end. 🙏

🎉 Huge congratulations to Daniel Fisch et al. Dr Eva Frickel 💚 on their groundbreaking discovery in Science Magazine!

science.org/doi/full/10.11…