“I believe this collaboration between a stem cell institute, a dental school, and experts in genetic sequencing and protein design could only happen in a few places, and one of them is in Seattle.”
UWDentalSchool Ruohola-Baker Lab Institute for Protein Design Brotman Baty bit.ly/4aIfBMT

Register today for this free SynBioBeta event: synbiobeta.zoom.us/webinar/regist…

We’re excited to share our preprint where we show, for the first time, the atomically accurate design of VHH antibodies!

We’re really happy to share our preprint demonstrating the atomically-accurate design of single-domain antibodies (VHHs) with RFdiffusion!

Structure-based VHH design preprint is now up! Nate Bennett Joseph Watson Rob Ragotte Andrew Borst and special shoutout to DeJenae See and Buwei who I collaborated with on this study. Watch this space closely, there's more coming :) Institute for Protein Design biorxiv.org/content/10.110…

Super excited to finally see the publication of this great paper in nature; this was one of the first projects I got to work on in grad school! Home Depot inspired #ProteinDesign Institute for Protein Design Work led by Tim Huddy Ryan Kibler Yang and Jinwei Xu
nature.com/articles/s4158…

📈 Read one of our recent most read #OpenAccess articles, 'Improving Protein Expression, Stability, and Function with ProteinMPNN' Jimenez-Oses Lab Institute for Protein Design CIC bioGUNE BRTA - Basque Research and Technology Alliance Ikerbasque

Read the article here ➡️ go.acs.org/7Kk

Our director David Baker recently shared his thoughts on the impact of AI on life sciences and healthcare startups. He spoke with Jenny Cronin at a UW CoMotion event.

ipd.uw.edu/2024/03/david-…

Protein design pioneer David Baker on why sharing code is key to building biotech startups.
Institute for Protein Design Charlotte Schubert GeekWire

bit.ly/49LEyGD

Paper is now live on Science Magazine! Congrats to Rohith Krishna Jue Wang Woody Ahern for leading this work. Big leap for protein modeling and design!

Paper: science.org/doi/10.1126/sc…

Code: github.com/baker-laborato…

Protein binding a small molecule designed with RFDiffusion-AA yesterday. I'm such a huge fangirl for these all-atom models. Baker Lab is awesome!

Signed.
A good idea for safety in protein design (AI powered or not): regulate and control the protein synthesis machines and firmware, not the AI research itself.
This is an idea I promoted at the UK AI Safety Summit.

Scientists are getting ahead of potential downsides of #AI for protein design. There are so many compelling and important uses for new #proteins #enzymes .
nytimes.com/2024/03/08/tec…

Our work on modeling and designing biomolecular assemblies is now in Science Magazine.
science.org/doi/10.1126/sc…
RFAA Code: github.com/baker-laborato…
RFdiffusionAA Code: github.com/baker-laborato…