If you're in the greater Longwood community in Boston, please feel free to come to my talk at Harvar Med (NRB 833) tomorrow at noon. If you are around a bit before or after and want to chat, let me know!

In this town hall #AACR24 event we focused on the importance of evolutionary thinking in early cancer detection. Wonderful discussion all around!

In this town hall #AACR24 event we focused on the importance of evolutionary thinking in early cancer detection. Wonderful discussion all around!

This is my new article! We start by developing a math modeling framework for evolution with nonlinear social interactions. We end up showing how natural selection affects the behavior collectives, not just individuals.

For Molecular Biology and Evolution's 40th anniversary, OfficialSMBE is launching a virtual issue of historic and contemporary contributions to the neutralist-selectionist debate. 'Neutral Theory and the Somatic Evolution of Cancer' written with Vincent Cannataro, was selected.

academic.oup.com/smbejournals/p…

You like digging into cool genetics data to understand cancer evolution?
We are recruiting a bioinformatics post-doc to work on oncogenesis in the oral cavity. This involves unique datasets on oral mucosa in diseased (oral cancer, Fanconi anaemia) and healthy subjects.

New research feat. step-wise scaled selection coefficients between normal esophagus and ESCC, epistasis analyses, and interesting findings regarding NOTCH1 and TP53 (and others)! Congrats to first-author Kira Glasmacher for leading this awesome work (as an undergraduate student!)

I found some cancer evolution research going on in a science lab in the new Starfield game! Extract heterogenous cells --> tumor growth (in vitro vs. in vivo) --> selective bottleneck (via therapy resistance) --> identify dominant clones.

Cancer Evolution, Early Detection, and Diagnosis:
Vincent Cannataro, Jimmy Lin, and Nita Ahuja will address this topic in a plenary session at the AACR Conference on Translating Cancer Evolution and Data Science (Dec 3-6, Boston).
bit.ly/3LefRbz
#AACRevol23 Vincent Cannataro

is honored to have been selected for the Yale School of Public Health Reducing Disease Risk Award, recognizing a recent paper by Vincent Cannataro Jeff Mandell and I, in which we attributed cancer origins to endogenous, exogenous, and preventable mutational processes.

academic.oup.com/mbe/article/39…

My advisor, Vincent Cannataro , and the other graduate student Jeff Mandell everyone

From Jeff Mandell Vincent Cannataro & Jeffrey Townsend,

AVAILABLE FOR YOUR USE:

our R package, cancereffectsizeR, which estimates neutral mutation rates and quantifies somatic variant selection.

aacrjournals.org/cancerres/arti…

Very happy to share our new resource report out in Cancer Research
doi.org/10.1158/0008-5…
The package organizes somatic variant data, facilitates a bunch of mutation rate breakdowns, and tests models of selection in evolving tissues. Incredible work by Jeff Mandell and Jeffrey Townsend!

Check out Jeffrey Townsend's fantastic Grand Rounds talk, which includes some of our collaborative work on calculating cancer effect size, and attributing these effects to mutational sources!

If twitter ends, let's follow each other on iNaturalist

Follow SARC tweetorialist Caralynn for #CTOS2022 patient perspectives

I'll be at #CTOS2022 with SARC and I'll be tweeting about things I learn there with patients and caregivers in mind.

Here's a little intro thread about me and why I'm at CTOS

Hey intro bio profs! Anyone teach biodiversity/evolution first semester then molecular/cell biology second semester? VS. molecules --> cells --> evolution/biodiversity? Do you have any resources (textbooks?) for someone thinking about starting off with diversity/evolution? Thanks

Hey intro bio profs! Anyone teach biodiversity/evolution first semester then molecular/cell biology second semester? VS. molecules --> cells --> evolution/biodiversity? Do you have any resources (textbooks?) for someone thinking about starting off with diversity/evolution? Thanks

Congratulations Vincent Cannataro Jeffrey Townsend