Jahanzaib Khwaja reports data from NAC revealing underestimation of disease-stage by biomarker-based staging for ethnic minorities in AL #Amyloidosis. Pts have a lower NT-ProBNP, Dx at younger median age 𝟱𝟕. Would affect trial inclusion/access & underestimate risk. #ISA2024

FDG PET/CT in #AL #amyloidosis Not an easy task with deaths happening over 6 months #ISA_2024 #Isa2024

Dr Julian Gilmore & Jahanzaib Khwaja w back-to-back talks showing instances of discordance between cardiac imaging (99MTC-DPD scint in ATTR & 18F-PET in AL, respectively) and clinical outcomes. Tricky space, important work. The International Society Of Amyloidosis #ISA2024

We just had a spectacular interview w/ Jahanzaib Khwaja at #ISA_2024 on ethnic disparities in AL #amyloidosis, the efficacy of dara-VTd in treatment-naive disease, and more! An absolute pleasure - head over to VJHemOnc.com/event/isa-2024 for some of our interview coverage!

Inflammatory diseases underlying AA n=959 🇬🇧 Helen Lachmann 🔸Rarer over time 🔸Age ⬆️ over time 🔸79% white 🔸⬇️RA 🔸⬆️ inflammation/chronic inflammation (proportion obesity) #ISA24 The International Society Of Amyloidosis

Last month, Part II of the DIDACT Foundation’s Clinical Trials Training Days took place, focusing on mentorship and collaboration. Equipping participants with essential skills and fostering a supportive environment for future clinical research leaders.🔬 leukaemiauk.org.uk/stories/the-uk…

#Myeloma Paper of the Day: Response rate & EFS to 2nd line dara/bortez/dex in relapsed/refractory light chain AL #amyloidosis after initial bortez-based regime are better if prior response was CR/VGPR & if relapsed disease vs. inadequate prior response: pubmed.ncbi.nlm.nih.gov/38840512/.

Novel trial designs Jurjen Versluis Examples of interim analyses for sample size re estimation/early stopping 🔸Conditional power (group sequential) 🔸Baysian: prior + posterior prob density based on observed data 🔹Use of external control data to increase sample size #EHA24

Join us on 21 September for a jam-packed programme aimed at empowering people affected by WM. As part of the day, we have four break out hugely interesting sessions, all concentrating on different aspects of living with WM. Book your tickets today: bit.ly/3VJHPAD

At #ISA2024, Jahanzaib Khwaja of UCLH spoke on the safety and efficacy of belantamab mafodotin in systemic AL #Amyloidosis. Watch the interview here: 👉 ow.ly/rHom50T9yVU 👈 #ISA_2024 The International Society Of Amyloidosis #ISA24 #ImmunoOnc #HemOnc

Apply for #EHACRTH European Hematology Association “Clinical #Research Training in #Hematology” provides early-researchers with a unique, year-long training and mentoring experience. Apply by September 24, 15:00 CEST. eha.fyi/CRTH2025

Yesterday, EHA #CRTH scholars moved from theory to practice, pairing to present each other's projects in only 2 minutes. Hoping to improve your presentation skills to pitch your clinical trial? The next call for CRTH is now open: eha.fyi/CRTH25

In addition to working on scientific skills for a future #clinicalresearch career, our #CRTH scholars and faculty also took time to share personal stories about work/life balance during an evening round table panel discussion. Learn more about how you can take part in next year's

That's the end of the final #CRTH workshop for this year's cohort. We would like to thank faculty and scholars for taking part in the Clinical Research Training in Hematology program and look forward to seeing their projects develop. Would you like to grow your career in

Looking forward to an exciting academic meeting as well as seeing friends and colleagues at the 11th UK Amyloidosis Workshop on Wednesday at Royal Free London with star guest speakers Sharmila Dorbala Cappelli Francesco and Prof arnaud Jaccard

Ever wondered what STRUCTURAL RACISM is? Important work from my friend Stephen Hibbs in JAMA Network Open Those with Duffy null associated low neutrophil counts are excluded from cancer trials + optimal therapy A🧵 @krutbvora, Chris Lathan, J Mark Sloan, Lauren Merz, Dr Vanessa Apea

It's not too late to get in-person or virtual tickets to hear from world-leading experts in WM care. This your unique opportunity to not only learn from some of the top voices in WM, but to ask these healthcare professionals questions! Book now: bit.ly/3VJHPAD