Dynamic coupling of cochlear inner hair cell intrinsic Ca2+ action potentials to Ca2+ signaling of non-sensory cells biorxiv.org/cgi/content/sh… #bioRxiv

Approximately 1 in 3 adults ages 65-74 has hearing loss. Many resources and devices can help. Learn more for Better Hearing and Speech Month: bit.ly/3MrkqxB #NIDCDinfo #BHSM

The National Institute on Deafness and Other Communication Disorders is seeking a Staff Scientist to serve as a laboratory leader who contributes to training and mentoring of all laboratory members. For more info visit go.nature.com/3PQC0xE. Open until filled. #NIH #stemjobs

The NIDCD Section on Structural Cell Biology seeks to hire a staff scientist with expertise in cellular biology & cryo-electron tomography. Applications will be reviewed starting August 1: bit.ly/3Mq36Zt #NIDCDjobs #NIHjobs

Spontaneous calcium transients in hair cell stereocilia biorxiv.org/cgi/content/sh… #bioRxiv

Transmembrane channel-like 4 and 5 proteins at microvillar tips are potential ion channels and lipid scramblases biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Hemifusomes and Interacting Proteolipid Nanodroplets: Formation of a Novel Cellular Organelle Complex biorxiv.org/cgi/content/sh… #biorxiv_cellbio

We are thrilled to share a truly exciting discovery by cryo electron tomography: the “hemifusome”- a new cellular organelle complex containing a hemifusion diaphragm! Tavakoli et al. biorxiv.org/content/10.110… Amirrasoul Tavakoli, shiqiong hu and @Becharakachar Tweetorial below (1/8)

We find members of the TMC family of putative #mechanosensors at the tips of #intestinal #microvilli! Bechara Kachar Modeling Angela Ballesteros and molecular dynamics simulations Sotomayor Lab at OSU suggest they may be ion channels and/or lipid scramblases, like TMC1 at #stereocilia tips!

Bravo!! Amazing work from my colleague on the organization and structure of respiratory complexes in native chlamy mitochondria using cryo-ET

(L) from "Direct observation of the rotation of F1-ATPase" Noji et al. 1997, doi.org/10.1038/386299… (R) "In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells" out today, doi.org/10.1126/scienc… What a time to be alive!!!

Simply beautiful

Pleased to announce our latest preprint: Genetically Encoded FerriTag as a Specific Label for Cryo-Electron Tomography. Great work of Wang Chang and Ioan Iacovache. doi.org/10.1101/2024.0… with great support of Dubochet Center for Imaging (DCI)-Bern and Microscopy Imaging Center Bern

Cytoplasmic ribosomes hitchhike on mitochondria to dendrites biorxiv.org/cgi/content/sh… #biorxiv_cellbio

Maturation and internalization of clathrin coated pits at the basal membrane of a BSC-1 cell as seen at 3.6 sec intervals and 84 nm resolution by total internal reflection structured illumination microscopy at 1.7 NA. Mature dome-like pits appear as rings because their distal

How myosin-I enhances pushing of branched actin networks, with Mengqi Xu, Michael Ostap and colleagues at UPenn, and modeling by David Rutkowski now published science.org/doi/10.1126/sc…

🎉Congratulations to Janelia Research Scientist Andy Moore (Andy Moore) on 2 honorable mentions in the 2024 #NikonSmallWorldInMotion competition for videos of a crawling tissue culture cell & a time-lapse of culture cells crawling & exploring. Nikon Small World

This is what Ebola viruses look like inside of infected cells. They look like tubes because the viral capsid is formed from proteins that directly bind to the linear, viral genome. "Until recently, it was impossible to reveal protein structures directly inside of virus-infected

Standing room only for the first ACB-Physiology combined seminar series given by Dr Ebrahim from UVA. She educated us on how the cytoskeleton uses mechanical forces to regulate cell secretion to reproduction. Outstanding! ECU Brody School of Medicine ECU Research ECU Office For Faculty Excellence The Geyer Lab