NEW PAPER: Published #openaccess in PLOS Global Public Health, we present the first estimates of the force of tuberculous infection in KwaZulu-Natal Province 🇿🇦 since the 1970s journals.plos.org/globalpubliche… Controlling M tuberculosis transmission is key to reducing the burden of TB disease [1/n]

You may hate the p-value, despise alpha-levels and be skeptical about confidence and credible intervals, by ignoring it all you have not managed to escape statistical uncertainty

A draft version of INSPECT-SR will soon be available. We are recruiting ppl to test the tool and give feedback in the production or update of systematic reviews of RCTs. Or, could apply to RCTs in an SR you've previously done. Contact me if interested!

Another issue that came up at #CCR24 was the #WinRatio method - a specific approach to handling composite outcomes in trials. 1/9 #MethodologyMonday #93

Andrew Althouse (Andrew Althouse) also did a super explainer video on the topic of win ratios a couple of years ago - well worth a listen! 9/9 x.com/cmichaelgibson…

Hoping to return one day Brennan Kahan Fan Li

Hoping to return one day Brennan Kahan Fan Li I’ll pay you three dollars (even bump it to euro exchange) if you tell me how you avoid informative cluster sizes?

Uri Shalit Brennan Kahan Hoping to return one day Michael Harhay I'd also call attention to this pre-print that explicitly defined possible estimands in SW-CRTs. arxiv.org/abs/2306.11267

📢Abstract deadline extension: the deadline for abstracts to the 10th Annual Meeting on Current Developments in Cluster Randomised Trials & Stepped Wedge Designs (13-14 Nov, Birmingham UK) has been extended to 5th July. Submit as Word/PDF to [email protected].

Remember if you're doing any clinical predictive #AI - model development or validation, then make your research is usable by reporting your study according to the TRIPOD+AI recommendations bmj.com/content/385/bm… #MachineLearning #ArtificialIntelligence #PredictiveAI

TWO NEW PAPERS in The BMJ on reporting recommendations for trials with surrogate outcomes (wonderfully led by anthony Muchai Manyara and Oriana Ciani) CONSORT: bmj.com/content/386/bm… SPIRIT: bmj.com/content/386/bm… #reporting #transparency #RCT

ASA History of Statistics Special Interest Group A summary of his contributions can be found here.... "Doug Altman: Driving critical appraisal and improvements in the quality of methodological and medical research" onlinelibrary.wiley.com/doi/10.1002/bi…

Please join us for the 🔥hot 🔥topic of synthetic data with its potential to assess clinical and cost effectiveness faster, if not also better. RDM Oxford The University of Edinburgh The University of Manchester University of Warwick NICE University of Liverpool MHRAgovuk Novo Nordisk Università di Padova Horizon Europe🇪🇺 and others

Delighted to introduce a new method for estimating a treatment policy estimand with missing data in clinical trials - **Retrieved Dropout Reference-Base Centred Multiple Imputation** onlinelibrary.wiley.com/doi/full/10.10…

Coming to ICTMC 2024? I'm running a pre-conference workshop on factorial trials with Alan Montgomery, Edmund the Just Jack 💙, and Sophie Hall. And if you can't make it, you can catch up on some of the course content in the recent CONSORT-factorial extension jamanetwork.com/journals/jama/…

Yes, it's true! I'm looking to recruit a new PhD student to work on cluster randomised trials with me - see the link below for more details. #Biostatistics #PhD

A couple of years ago I thought it might be fun to start the week with a tweet about some aspect of trial, or related, methodology - tagged #MethodologyMonday. 100 topics later, I hope you have found some of them useful. Here is a list of the topics so far 1/2

We'll be running a workshop on factorial trials at ICTMC 2024 - come along to find out about all the new research Marion Campbell describes below! ictmc.org/wp-content/upl…

Come and work with Aris Perperoglou, Adrian Mander, Ruth Keogh and I on a 3 year Knowledge Transfer Partnership between GSK and London School of Hygiene & Tropical Medicine. More details here: jobs.lshtm.ac.uk/vacancy.aspx?r…

sciencedirect.com/science/articl… Stage 1 of the INSPECT-SR project, now published in Journal of Clinical Epidemiology