Nguyen Ngoc Uyen Nhi
@nhinguyen1984
ID: 1519331865777348609
27-04-2022 15:06:01
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39 Followers
72 Following
Nicholas Lam,Nguyen Ngoc Uyen Nhi et al. show that genetic or pharmacological inhibition of #calcineurinB1, with U.S. FDA approved #FK506, promote #cardiomyocytes proliferation in adult mice Hesham Sadek #CardiacRegeneration 👉rdcu.be/cRyp6
Happy to share our paper on the role of CN in heart regeneration. Really proud of Nicholas Lam and Nguyen Ngoc Uyen Nhi for an outstanding job as they worked together to figure out why CN deletion induced heart regeneration but pharmacological inhibition did not.
Several postdoc positions are available in the Sadek Lab. Candidates with expertise in molecular biology, biophysics, cardiac physiology and drug discovery/synthesis are encouraged to apply. Contact me directly @ [email protected]. Please spread the word/retweet.
Excited to share our recent work where we identify two FDA-approved drugs that induce heart regeneration in small and large animals. Outstanding work by Mahmoud Salama Ahmed and Nguyen Ngoc Uyen Nhi! Bringing regenerative therapies a step closer to the clinic rdcu.be/dANtR
A study led by Hesham A. Sadek, M.D., Ph.D., at #UTSW, is the first to identify FDA-approved drugs that can activate endogenous regeneration pathways and restore cardiac function in animal models after a heart attack. Nature Cardiovascular Research go.nature.com/3PgPTGs #ScienceTwitter
Research| Ahmed, Nguyen, et al. identify paromomycin and neomycin as candidates and validate that the combination of these two #antibiotics promotes cardiomyocyte proliferation and improves cardiac function post-#myocardialinfarction. Hesham Sadek 👉rdcu.be/dBcfZ
Feng Xiao spent 8 years trying to find out how cardiomyocytes disassemble their sarcomeres during mitosis. Grateful for her dedication and to Nguyen Ngoc Uyen Nhi who took on the difficult task of finishing this project. Thankful for our wonderful collaborators. bit.ly/3UP82hO