Behold: Heterotypic nucleosomes show that H3 tail acetylation in cis precedes H3K4me3 !!! Mobilization of the substrate histone tail (most likely by charge neutralization) is key ... Dr. Brian D. Strahl EpiCypher, Inc. Kanishk Jain [biorxiv.org/content/10.110…]

Congrats to graduating seniors of the Dr. Brian D. Strahl lab! We’re so proud of all of you and will miss you! Aakanksha Gundu, McGuire Metts, Lara van der Maas, and Aman Mengistalem Amanuel Mengistalem

We are proud to announce the publication of the cis-acting proteoform-based mechanism that links Histone H3 acetylation and H3K4me3. Proteoform mechanisims are crucial to gene transcription! #proteoforms #proteomics #epigenetics #chromatin #transcription doi.org/10.7554/eLife.…

Had a wonderful evening out with the Dr. Brian D. Strahl lab today! Great food and trivial pursuit! Lab socials can be pretty fun :)

It was a huge honor to be the student-nominated speaker at Purdue yesterday. It’s common for students to meet the speaker at lunch but I was blown away with the turnout! I had an great time meeting colleagues and all the students. Thank you so much for having me out!

Had a blast presenting my work on PHRF1 and talking epigenetics at #epi2023! Thanks for a great conference, EpiCypher, Inc.! Dr. Brian D. Strahl Abid Khan

Fantastic collaboration with the Musselman lab that shows why those pesky histone PTMs don't always appear to play together : been looking in the wrong place / way : Nucleosomes don't just CARRY the tails - they regulate their use ...

⁦Journal of Biological Chemistry⁩ symposium ⁦ASBMB⁩ meeting kicked off by ⁦⁦Editor-in-Chief of JBC⁩ , and composed by three outstanding talks by editors and scientists ⁦Henrik Dohlman⁩ ⁦Dr. Brian D. Strahl⁩ ⁦⁦Kirill Martemyanov Lab⁩.

Really lucky and proud mentor of Phu, an exceptionally talented undergrad from Dr. Brian D. Strahl lab, who also just won a summer research fellowship (SURF)! UNC Biochemistry and Biophysics department

Happy mentor moment everyone! I'm am excited to announce that Kanishk Jain has just accepted a faculty position at University of Minnesota....Woohoo!!! I am so proud of his accomplishments and am excited for the future Jain Lab coming in 2025!

Hear the newest unpublished research on biological methylation and develop your career at this year's #BIOMSRC. Davies Lab - CH3, Dr. Brian D. Strahl, Van Rechem Lab, and Kai Ge have developed an amazing program! See the full agenda and save your space: hubs.ly/Q02tsJ8G0

UNC Office for Undergraduate Research JDowen Lab Dr. Brian D. Strahl Abid Khan Gaorav Gupta At the 25th Annual celebration of undergraduate research UNC Office for Undergraduate Research Brett Smith of the Strahl lab Dr. Brian D. Strahl presented a poster entitled “Acetylation-mediated histone H3 accessibility by chromatin modifiers” 5/8

Check out our preprint follow-up story from Dr. Brian D. Strahl's and Dr. Nicolas L. Young's labs on H3K4 methylation and histone tail accessibility. This is my former rotation mentee, now labmate Geo Fox's first first-author manuscript, working closely with Karl Poncha (Young Lab).

Great time with great people at Strahl lab party tonight! Thanks for having us, Brian! Dr. Brian D. Strahl Kanishk Jain

Major Congrats to Ethan Madden and Kit Cummings for being awarded a Curriculum in Genetics and Molecular Biology Fellowship! Great job and thank you UNC Genetics PhD for your support!

Congrats to all involved and thank you for an incredibly streamlined review process, Journal of Biological Chemistry! Dr. Brian D. Strahl Geo Fox Dr. Nicolas L. Young

Just shared my main postdoctoral work in Dr. Brian D. Strahl’s lab at the #BioMethylSRC and advertised for my new lab at UMN! I’m delighted to have such wonderful colleagues with whom I can continue sharing exciting stories about chromatin and histone PTMs.

Just 2 postdocs from Dr. Brian D. Strahl’s lab (current: me; former: Scott Rothbart) with their mentor. Looking forward to joining Scott on the former postdoc/current PI list by the next #BioMethylSRC