David Denning(@dwdenning) 's Twitter Profileg
David Denning

@dwdenning

Advocate for better health for those with fungal disease; Founder of GAFFI and Prof of Infectious Diseases in GH, Manchester.

ID:420263585

linkhttp://www.gaffi.org calendar_today24-11-2011 11:50:57

746 Tweets

2,6K Followers

1,2K Following

@MFIG(@UofMMFIG) 's Twitter Profile Photo

One of the latest MFIG papers in collaboration with Mycology Reference Centre Manchester on a novel mycobiome diagnostic in BMC

bmcmicrobiol.biomedcentral.com/articles/10.11…

account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Candida glabrata debate. As a top 12 fungal pathogen of man, consequential name changes need consultation. How were the medical, public health and pharma communities consulted? They were not. So this taxonomic decision-making is flawed, esp. when it affects disease nomenclature

Candida glabrata debate. As a top 12 fungal pathogen of man, consequential name changes need consultation. How were the medical, public health and pharma communities consulted? They were not. So this taxonomic decision-making is flawed, esp. when it affects disease nomenclature
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Should Candida glabrata have its name changed? In my view - no. Too disruptive to public health communication about the importance of Candida infections. Read the historical arguments here: shorturl.at/tGO56

account_circle
GAFFI(@gaffi_org) 's Twitter Profile Photo

Diagnostics deficiencies for fungal diseases is the theme in Nature’s series on NTDs. nature.com/articles/d4158… quotes - Banda Peru, Charkrabarti India, Louenco Rodrigues Brazil, Seyedmousavi USA and GAFFI: “it should be possible to provide low-cost diagnostics around the world”

account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Slide presentations from Advances Against Aspergillosis and Mucormycosis now available on The Aspergillus Website and what a rich feast these talks are! Stunning range of science and medical practice!
aspergillus.org.uk/slide-presenta…

Slide presentations from @AAAMConference now available on The Aspergillus Website and what a rich feast these talks are! Stunning range of science and medical practice! aspergillus.org.uk/slide-presenta…
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Outcome from mucormycosis varies by drug therapy & surgery. Just out in OFID: shorturl.at/kmRZ3. AmB alone =31.5% mortality. Posaconazole alone = 17.2%. AmB + posaconazole or isavuconazole = 6.6% mortality. Should dual combination Rx be routine? Only retrospective data.

Outcome from mucormycosis varies by drug therapy & surgery. Just out in OFID: shorturl.at/kmRZ3. AmB alone =31.5% mortality. Posaconazole alone = 17.2%. AmB + posaconazole or isavuconazole = 6.6% mortality. Should dual combination Rx be routine? Only retrospective data.
account_circle
Advances Against Aspergillosis and Mucormycosis(@AAAMConference) 's Twitter Profile Photo

That's a wrap on Day 3 of ! 🎉

What an incredible journey through cutting-edge research and expert discussions. A huge thank you to our committee, faculty, speakers, attendees and everyone who made a success. 🙌

Up next... ! 📆 David Denning @gangneuxjp

That's a wrap on Day 3 of #AAAM24! 🎉 What an incredible journey through cutting-edge research and expert discussions. A huge thank you to our committee, faculty, speakers, attendees and everyone who made #AAAM24 a success. 🙌 Up next... #AAAM26! 📆 @dwdenning @gangneuxjp
account_circle
animesh ray(@animeshraydoc) 's Twitter Profile Photo

1/2
An intriguing problem - which we tried to systematically examine in our new study was the effect of varying volumes of saline instillate on BAL-GM level.

onlinelibrary.wiley.com/doi/full/10.11…

The crux is highlighted in video below. A big shout-out to Anuj for his efforts!

account_circle
Advances Against Aspergillosis and Mucormycosis(@AAAMConference) 's Twitter Profile Photo

Wrapping up an incredible first day at ! 🌟

A day filled with enlightening talks, vibrant discussions, and global networking. 🌐 Thanks to our fantastic speakers, engaged audience, and co-organisers David Denning and @gangneuxjp.

Get ready to dive back in tomorrow!

Wrapping up an incredible first day at #AAAM24! 🌟 A day filled with enlightening talks, vibrant discussions, and global networking. 🌐 Thanks to our fantastic speakers, engaged audience, and co-organisers @dwdenning and @gangneuxjp. Get ready to dive back in tomorrow!
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

For those unable to travel to Milan, online registration is possible and free for those from low and low-middle countries. Join us and participate in real time or after the event, once registered.

account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Global burden of severe fungal disease: annual new cases of chronic pulmonary aspergillosis = 1.8M & global prevalence of 6.1M. Incl. dual TB/CPA cases, TB misdiagnoses, early CPA cases during TB therapy, & later CPA in lung cavities. Mortality of 340,000 thelancet.com/journals/lanin…

Global burden of severe fungal disease: annual new cases of chronic pulmonary aspergillosis = 1.8M & global prevalence of 6.1M. Incl. dual TB/CPA cases, TB misdiagnoses, early CPA cases during TB therapy, & later CPA in lung cavities. Mortality of 340,000 thelancet.com/journals/lanin…
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Global burden of IFIs: HIV/AIDS infections number 642,000 with ~327,000 deaths, about 50% of all AIDS deaths, many mistaken for TB. Pneumocystis pneumonia 400k, cryptococcal meningitis 152k, disseminated histoplasmosis 71k, talaromycosis 19k. thelancet.com/journals/lanin…

Global burden of IFIs: HIV/AIDS infections number 642,000 with ~327,000 deaths, about 50% of all AIDS deaths, many mistaken for TB. Pneumocystis pneumonia 400k, cryptococcal meningitis 152k, disseminated histoplasmosis 71k, talaromycosis 19k. thelancet.com/journals/lanin…
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Global burden of IFIs: est. 626,000 have candidaemia (7.8/100,000 pop.). As blood culture is ~40% sensitive, probably another 150% cases or 939,000. Given so many undiagnosed cases, likely mortality 995,000 (63.6%). thelancet.com/journals/lanin…

Global burden of IFIs: est. 626,000 have candidaemia (7.8/100,000 pop.). As blood culture is ~40% sensitive, probably another 150% cases or 939,000. Given so many undiagnosed cases, likely mortality 995,000 (63.6%). thelancet.com/journals/lanin…
account_circle
David Denning(@dwdenning) 's Twitter Profile Photo

Global burden of IFIs: 2 113 000 people develop invasive aspergillosis related to COPD, intensive care (incl. annual influenza), lung cancer, or haematological malignancy & after alloHSCT with a crude annual mortality of 1 801 000 (85·2%). thelancet.com/journals/lanin…

Global burden of IFIs: 2 113 000 people develop invasive aspergillosis related to COPD, intensive care (incl. annual influenza), lung cancer, or haematological malignancy & after alloHSCT with a crude annual mortality of 1 801 000 (85·2%). thelancet.com/journals/lanin…
account_circle
GAFFI(@gaffi_org) 's Twitter Profile Photo

After 12 years, a comprehensive reassessment of annual incidence of severe fungal disease finds 6.5M affected with 3.7M deaths. ~68% of deaths directly attributable. 2x prior mortality estimate. Lack of suspicion & diagnosis the largest factor in deaths. gaffi.org/media/news/

account_circle
Advances Against Aspergillosis and Mucormycosis(@AAAMConference) 's Twitter Profile Photo

Join us later this month in Milan for the 11th AAAM conference 🤩

Led by field experts like David Denning and JP Gangneux, this is an event you don't want to miss!

Whether you choose to attend in person or online, book now to avoid disappointment! 👇
ow.ly/Mkkl50Qo7hS

Join us later this month in Milan for the 11th AAAM conference 🤩 Led by field experts like @dwdenning and @GangneuxJp, this is an event you don't want to miss! Whether you choose to attend in person or online, book now to avoid disappointment! 👇 ow.ly/Mkkl50Qo7hS
account_circle