Tyypin 1 diabetesta voidaan hoitaa kantasolusaarekkeilla. Turun ja Helsingin yliopistojen tutkijat ovat kehittäneet menetelmän, jolla voidaan parantaa näiden solukorvaushoitojen tehoa ja turvallisuutta. #diabetes Turku PET Centre Väinö Lithovius utu.fi/fi/ajankohtais…

Teresa Rayon Sergio Menchero Diego Balboa @biomedicum_helsinki Thank you for visiting and giving a fantastic talk! 💎

The RFX6 gene mutation impairs insulin secretion and increases the risk of type 2 and gestational diabetes. University of Helsinki Hazem Ibrahim OtonkoskiLab helsinki.fi/en/news/diabet…

Today in Science Magazine, together with my former colleagues at NIBR, we report the discovery and characterization of first molecular glue degraders of the WIZ transcription factor (TF) for fetal hemoglobin derepression and therapeutic consideration in Sickle Cell Disease. 1/10

Suomessa muuta maailmaa yleisempi geenimuunnos heikentää insuliinin eritystä ja lisää riskiä sairastua kakkostyypin diabetekseen sekä raskausdiabetekseen. University of Helsinki Hazem Ibrahim OtonkoskiLab helsinki.fi/fi/uutiset/dia…

Excited to share my latest review on genetically-encoded fluorescent redox biosensors! 🧬✨🧪🔬. Free to access until 23rd August following this link authors.elsevier.com/a/1jNDOw0NWL9V

Come to try some fun games and talk about embryo development and embryo models at the The Royal Society summer science exhibition! It's only until Sunday, don't miss it 🙌

A fun post by yours truly, on a population of cells that's close to my heart: the lateral line of #zebrafish. Thanks to the Node for the opportunity. #DevBio forever! thenode.biologists.com/ready-steady-c…

Tutkijat loivat solun, josta ei voi syntyä syöpää. Tutkimusryhmä, yhteistyössä HUS Helsingin yliopistollinen sairaala, onnistui luomaan soluja, joiden jakautumista voidaan kontrolloida. Menetelmä mahdollistaa uudenlaiset, turvalliset soluhoidot. Kirmo helsinki.fi/fi/uutiset/gee…

Scientists create a cell that precludes malignant growth. Researchers succeeded in creating cells whose proliferation can be controlled. The technique enables new and safe cell therapies. HUS Helsingin yliopistollinen sairaala Kirmo helsinki.fi/en/news/genes/…

1/10 Our latest article, now available in Molecular Therapy👇, tackles one of the main concerns related to cell-based therapies: uncontrolled cell proliferation. In a world of TLDRs, here's a breakdown in 10 simple twits 🤓

4/10 🔬 Our approach to prevent this used #CRISPR-Cas9 to knock out the TYMS gene. Thus, we have generated cells that proliferate when supplemented with thymidine but fail to proliferate in its absence ✨ #GeneEditing

5/10 🧫 The knockout had minimal or no impact on iPSCs metabolism, pluripotency and genomic integrity. 🐭 In mice, TYMS−/− iPSCs formed teratomas only when supplemented with thymidine, further supporting the in vivo safety provided by the approach #InVivoStudies

Excited to share our publication in Science Translational Medicine. Harmine and exendin-4 combination therapy safely expands human β cell mass in vivo in a mouse xenograft system. science.org/doi/10.1126/sc…

We put our novel UDP-GlcNAc quantification method to use and helped French colleagues with their interesting hepatocellular carcinoma study. Intriguing connections to our own ongoing projects. Folkhälsan Research Center STEMM Research Program Medicine and Health, University of Helsinki Life Sciences University of Helsinki journals.lww.com/hep/abstract/9…

Exciting news! The review ⁦(O.⁩) about “Periphery/brain interactions in obesity” is out today in ⁦⁦Nature Metabolism⁩ 🎉 Helmholtz Diabetes Center (HDC)⁩ IDO⁩ ⁦Universität München⁩ ⁦Deutsches Zentrum für Diabetesforschung (DZD)⁩ ⁦Munich Cluster for Systems Neurology (SyNergy)⁩ nature.com/articles/s4225…

New Paper! Jonathan Baldan, Juan Camacho and Marta Ballester from the lab find a genetic program driven by Sox4 promoting the resolution of tissue injury in pancreas regeneration and cancer. Jonathan Baldan Gastroenterology Biotech Research & Innovation Centre (BRIC) #tuft_cells #plasticity tinyurl.com/4vssyzdt

🔵We are seeking a new director! The Centre for Genomic Regulation (CRG) is an independent research institute located on the shores of the sunny beaches of Barcelona. It is part of the public Centres CERCA research system of Catalonia. We have one clear mission: to understand the

We are very grateful for the support from the European Innovation Council because is a huge impetus for Integra Therapeutics and our #FiCAT advanced therapies platform. I am pleased to see an increased in the #women led companies chosen by #eicAccelerator   #EUeic #STEMWomen #WomenInBusiness

We present The Transcription Factor Binding Landscape of Mouse Development🐭🧬 #DevBio We use CUT&RUN-LoV-U to map Many SignalingPathways X 4tissue X 2stages It is a huge dataset - yet only the beginning of the TranscriptionFactorBinding(TFB)-OMICS biorxiv.org/content/10.110…