Happy to share the Weis lab’s latest work on Wnt signaling! science.org/doi/10.1126/sc… We found that the lipid PI(4,5)P2 is critical for recruiting the transducer protein Dishevelled to the membrane during pathway activation. Thread below:

Had the best time at CSHL cryo-EM course 2023 -- so much knowledge gained, awesome connections made and overall an inspiring couple of weeks. Huge thanks to the course instructors, lecturers and fellow students Lander Lab kollman lab Jennifer Cash CSHL Courses #cryoEM

Last October, cell biology lost one of its brightest stars, Bill Weis. Bill was a masterful biochemist and structural biologist who made landmark contributions to a remarkable number of fields. An obituary from Mark Peifer & Alexander Dunn in JCellBiol: hubs.la/Q02m3W3N0