Happy to announce 1st of several papers/preprints to drop from our lab, by Cerise Tang and co-led by Justin Jee. The first 1-figure paper I've written but not the last, the title says it all: Obesity shapes the selection of driver mutations in cancer medrxiv.org/content/10.110…

If you are curious about #micronuclei, their role in #cancer and how to exploit their aberrant biology to improve #therapy and #diagnosis, me and Samuel Bakhoum address this and much more in our newly published review in Cancer Discovery!

Beautiful morning in San Diego! I am excited to present our latest work on genome instability in ovarian cancer. Looking forward to a fantastic session with Samuel Aparicio McClelland Lab Marcin Imieliński (12:15-14:00 PT, Room 29 Conv Center). eppro01.ativ.me/appinfo.php?pa… #AACR24

Dr. Ignacio Vázquez spoke at a major symposium about evolutionary dynamics of whole-genome doubling in #ovariancancer at #AACR24. Learn more: bit.ly/3VUiA07

Early career researchers: Please join us for the 2024 Single-Cell Cancer Biology Gordon Research Symposium in June! We still have some spots open for oral presentations - apply by April 30! More info below ⬇️ grc.org/single-cell-ca…

We are only one month away from the Gordon Research Conferences GRC+GRS in Single-Cell Cancer Biology! We have a fantastic program lined up! A few spots left. Register now! 🔥 GRS: June 8-9 (early career)🔥 grc.org/single-cell-ca… 🔥 GRC: June 9-14 (main conference) 🔥 grc.org/single-cell-ca…

I thought my 2 year old was going through a sleep regression at 5 am, but no, he just wanted to let me know that our lab's newest work with Sohrab Shah and led by Minsoo Kim was finally online Nature Genetics nature.com/articles/s4158…

Thrilled to announce that my PhD thesis work has been published in Nature Genetics! 🎉 Huge thanks to my advisors, Sohrab Shah and Ed Reznik, for their guidance and support throughout the years!

Our first of a pair of reviews on #Chromosomal_Instability is out in ⁦NatureRevClinOncol⁩ on targeting CIN in patients with #cancer written with the amazing ⁦Duaa Al-Rawi, MD PhD⁩ ⁦Emanuele Lettera⁩ ⁦Jun Li⁩ ⁦Melody Di Bona⁩ nature.com/articles/s4157…

Thrilled that #SAVANA is out🥳 biorxiv.org/content/10.110…, our method to analyse somatic SVs, allele-specific copy number aberrations (SCNAs), tumour purity & ploidy in clinical samples using #long-read sequencing Oxford Nanopore PacBio! 😮 Comparisons of long/short reads & algorithms👇

Our team at The Halvorsen Center for Computational Oncology has an open position for an experienced AI scientist to work on multimodal analyses of real-world cancer data. Please apply using this link, or forward to others who may be interested. social.icims.com/viewjob/pt1722…

On bioRxiv today, we raise serious concerns over a recent @nature paper describing ReDeeM, a new single-cell mitochondrial DNA (mtDNA) sequencing / analysis method. Here are three things that you need to know: 1/n biorxiv.org/content/10.110…

If you have an mtDNA tracing dataset, regardless of the technology or stage of the project, I will review your workflow/results/interpretation within 1 week--provided the code and data are made available in public (e.g., GitHub) and discussion also occurs on a public forum. 7/n

Peter Campbell leaves the Sanger Institute at the end of the year to become Quotient's CSO. A mentor and one of my favourite scientists. His foundational, profound and creative contributions to cancer genomics and somatic evolution have truly shaped those fields. [1/7]

18 years ago, I came to the US to pursue my dream of becoming a scientist. Last week marked a major milestone in this journey, as I accepted an Assistant Professor position at The University of Chicago, where I am thrilled to start my own research group in January 2025! (1/5)

Ever wondered why cancer cell micronuclei rupture irreversibly? The answer is in my first-author paper in the Samuel Bakhoum lab and its back-to-back companion from Stefano Santaguida lab out today in Science Magazine and featured on its cover ✨(1/6) science.org/doi/10.1126/sc…

1/n 🚨 🧬Our paper on the role of #mitochondria and free radicals in promoting the collapse of #Cancer #micronuclei is out in Science Magazine today. A story led by the brilliant Melody Di Bona it started with a simple question: why do micronuclei rupture? science.org/doi/10.1126/sc…

Super excited to announce our new framework to store, integrate, and analyze genetic and clinical data under a secure framework by leveraging blockchain technology : nature.com/articles/s4159… lead by brilliant student Ahmed Elhussein Columbia DBMI (1/n)

Thrilled to announce that I’ve been awarded an #ERCStG by the European Research Council (ERC)! We aim to uncover the timing and mechanisms of mammalian male germline mutation, as well as explore how primates lower their somatic mutation rates. The lab will be hiring soon—stay tuned!