Celebrating the illustrious career and retirement of Angie Falco today. 40 years of serving patients (mainly with blood cancer/MM) as an RN and then nurse practitioner. It’s been amazing working with her and will miss her greatly.

Where are my fellow #medtwitter & #lymsm sci-fi/fantasy readers at? cc Powell's Books

NEW: Response-adapted ultra-low-dose 4 Gy radiation as definitive therapy of gastric MALT #lymphoma : a single-centre, pilot trial MD Anderson Cancer Center #lymsm
thelancet.com/journals/lanha…

During #ASCO24 , we spoke with manalikamdar, of CU Anschutz Medical Campus/CU Anschutz Division of Hematology, to hear results from the pivotal phase III TRANSFORM study on liso-cel versus standard of care in patients with relapsed or refractory large B-cell lymphoma. #LBCL

📺 Watch here: buff.ly/3wW6Ujv

Great to see the escBEACOPDac data on MedRxiv. Procarbazine is genotoxic - much less so with dacarbazine and clinical outcomes similar.

So until BreCADD funded, it's escBEACOPDac when intensive chemo needed in Hodgkin.

medrxiv.org/content/10.110…

We're excited to open the phase 3 randomized trial of sonrotoclax/zanubrutinib versus venetoclax/obinutuzumab in untreated CLL/SLL at CU Anschutz Medical Campus. Learn more at our CU Anschutz Division of Hematology clinical trials page below. cc manalikamdar #lymsm
medschool.cuanschutz.edu/hematology/all…

Please do check out our other published books as well. All proceeds go to support the website hosting costs of in-Training and our other online #meded publications.
Lulu: lulu.com/spotlight/page…
Amazon: amazon.com/s?k=pager+publ…
B&N: barnesandnoble.com/s/%22Pager+Pub…

Reviewing proof copies today for our latest book: The Perfect Doctor, a compilation of 40 essays curated by Dr. Sasha Yakhkind. Published by pagerpublications.org, our 501c3 non-profit publishing house. Available at major retailers soon! #meded #medhum

🙌 Agree, esp. regarding the use of checkpoint inhibitor therapy during pregnancy (ncbi.nlm.nih.gov/pmc/articles/P… w/ Elad Sharon)

👉Also, INCIP (International Network on Cancer, Infertility and Pregnancy) is a great cross-tumor global collaborative doing this: cancerinpregnancy.org

Um, looks like people who were in Chicago #ASCO24 this week were too happy! 😁

#NLPHL case for #lymsm : teenager dx with Stage IIA (cervical, axillary) NLPHL 2.5 years ago. At that time, received ritux x 6. Ultrasound now shows unilateral cervical adenopathy, 5.2 cm. If relapsed limited-stage NLPHL diagnosed... cc Jamie Flerlage Michael Sargent Binkley

Long-term follow-up from ECHELON-1: PET2+ in BV-AVD arm definitely not as prognostic as ABVD arm. #ASCO24 #lymsm

BV-CHP for CD30 <10% ALCL PTCL #ASCO24 :
- 74 pts, 43% CD30 <1%
- ORR 65% for <1%, 82% for 1-10% (if centrally reviewed) #lymsm cc Brad Haverkos

Glofitamab retreatment data #ASCO24 :
- 13 pts, various histologies
- 5 pts had ongoing responses after pretreatment (2 FL, 2 MCL, 1 tFL)
- DLBCL/HGBL responses quite poor
Maybe retreatment paradigm not so good for aggressive dx... #lymsm

excited to see this out today - looking at deficiencies in PRO/QOL reporting in pivotal heme malignancy trials!

A systematic review of phase III clinical trials of hematologic cancers found that there is widespread collection of patient-reported outcomes (PROs), but limited reporting of PRO data in associated primary trial publications, suggesting publication bias. ja.ma/3VowerM

Areej El-Jawahri with a first I’ve seen ASCO #ASCO24 simultaneous laughs and applause for a successful intervention to improve sexual function for patients who received stem cell transplant

Slides speak for themselves

Ajay Major, MD, MBA Thomas LeBlanc, MD, MA, MHS, FAAHPM, FASCO For those in the cheap seats in the back:

📣 “…And only PATIENTS can tell us if those symptoms are tolerable and if they interfere with daily functioning”

(thought it bore repeating)

👆🏻 Great study to check out

#ASCO24 #PalliativeCare #hapc #PalOnc #hapc #PallOnc #QOL

Continued treatment = ⬆️ burden in all aspects. MRD2STOP addresses the long standing question of maintenance deescalation in #mmsm . AND incorporates CD138-enriched NGS to achieve MRD 10^7 sensitivity! PLUS shows improved QoL and $21 million in cost savings!