Christian Münch (@muenchlab) 's Twitter Profile
Christian Münch

@muenchlab

Endowed Lichtenberg-Professor @goetheuni

Biochemistry, proteomics, cell and systems biology of proteostasis and cellular stress responses in ageing and disease

ID: 1198878366415380480

linkhttp://pqc.biochem2.de calendar_today25-11-2019 08:18:02

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Christian Münch (@muenchlab) 's Twitter Profile Photo
Christian Münch
@muenchlab

a year ago

I am happy to propose a model for mammalian #mitochondria UPR signaling, published nature. nature.com/articles/s4158… Mito protein misfolding induces two cytosolic signals –mtROS and mito protein precursor accumulation. These activate the mito UPR via a DNAJA1-HSF1 signaling axis.

I am happy to propose a model for mammalian #mitochondria UPR signaling, published <a href="/Nature/">nature</a>. nature.com/articles/s4158… Mito protein misfolding induces two cytosolic signals –mtROS and mito protein precursor accumulation. These activate the mito UPR via a DNAJA1-HSF1 signaling axis.