It is with great sadness we inform you of the passing of Dr. William Roberts, a renowned scientist, physician, and editor. His profound impact will be forever remembered.

We extend our heartfelt condolences to his family, friends, and colleagues during this difficult time.

(1/3) Don’t give up too early on statins.

Assess nonadherence, check LDL-C levels to monitor, remember not all nonadherence is “forgetting”.

Sometimes, patients intentionally stop statins (50% after 1.5 years).

Support patients by building trust in our care team.
#CardsJC

Keith C. Ferdinand, MD, FACC, FAHA, FNLA Such important points! Statins are #1, #2, and #3 then other options!

FINAL | UCLA 68, Northwestern 63

This team fought and clawed until the very end. A season we will never forget 💜

Do informatics based interventions aid in #statin use & implementation of #EBM in healthcare systems? Accord. to this #LBCT #ACC23 by Salim Virani — the answer is yes! (More secondary analysis on alert fatigue pending)

ahajournals.org/doi/abs/10.116…

Congratulations Salim Virani et al. 🫀

Sterologists: Here are the Part 3 steps in the cholesterol synthesis pathways. It terminates with the production of the aliphatic (linear, nonaromatic) 30 carbon cholesterol precursor called squalene National Lipid Association European Atherosclerosis Society International Atherosclerosis Society (IAS)

Simon Hill MSc, BSc (Hons) CARDIA is a great study showing that both LDL size &LDL composition is what determines apoB. Most importantly, apoB was better predictor than LDL-C & NON-HDL-C - here are my slides

For lipid geeks or sterologists - I will be posting a series of slides illustrating the very complex steps involved with the production of cholesterol - it is ~ 37 steps that can be grouped into 4 steps. This slide is an overview - National Lipid Association European Atherosclerosis Society International Atherosclerosis Society (IAS)

Sterologists: The part 4 steps of the cholesterol synthesis pathway with evolution of various aromatic molecules from lanosterol to cholesterol via 2 pathways. The penultimate precursor molecules desmosterol & cholesterol serve as markers of synthesis National Lipid Association European Atherosclerosis Society

#STOPCA trial #lbct #ACC23 #WCCardio #CVPrev #primaryprevention
Do statins ⬇️ cardiotoxic effects of anthracyclines in Lymphoma pts?
♥️atorvastatin 40 mg prior to chemo
♥️High doses of anthra given
♥️3 fold less ⬇️ EF w/ statin Tx vs placebo: safe, effective
Not HF🏥 but EF

'Hyper-response' to statins typically occurs in those who are hyper-synthesizers of cholesterol (check lathosterol & desmosterol levels before Rx) or those with hypo-absorption (sito- / campesterol). Tests are available BostonHeartDX or DTC at empowerDX European Atherosclerosis Society Prakash Sanzgiri

Well, that was #informative , #scholarly , #inspiring , #warm , #fun . What a force in prevention Pamela B Morris MD MUSC Cardiology THANK YOU! Extending best wishes from all of us NM Cardiovascular Neil Stone Don Lloyd-Jones John T Wilkins, MD Sarah Hale

Very thankful to win this award, to be presented #ACC23 . Exceptionally thankful to my mentor Faraz for letting me work on this. Glad to showcase the multidisciplinary work being done in our Center for AI! James D Thomas, MD Clyde Yancy, MD, MSc Jane Wilcox, MD, MSc Sanjiv J. Shah, MD Akhil Narang, MD

Cardiologist Martha Gulati named chair of women’s cardiovascular medicine and research at Cedars-Sinai #cardiology #cardiotwitter Cedars-SinaiMed Dr. Martha Gulati ♥️🫀❤️‍🩹🇨🇦 ASPC ow.ly/fBeA50MvyPW

Coronary Artery Lesion Lipid Content and Plaque Burden in Diabetic and Nondiabetic Patients: PROSPECT II ahajournals.org/doi/10.1161/CI…. Useful reference to underscore why lipid guidelines emphasize focused primary prevention in those w DM. Preventing 1st MI is all important

Memories: There is no prayer I would have mastered Internal Medicine or passed the ABIM certification without living with the 7th Edition (1974) of Harrison's textbook during my residency. My entire book, like lipid page below is underlined in red ink

Longer life expectancy & lower cancer risk in Seventh-Day Adventists mol.im/a/7731947 via Daily Mail Online Plant-based diet and nuts for snacks!

I’m happy to share that I’m starting a new position as Director of Mount Sinai Heart at Mount Sinai Health System! lnkd.in/e8J-7VAT

Ode to Korotkov
jamanetwork.com/journals/jamac… JAMA Cardiology

This. This is outstanding! ☺️ NM Cardiovascular McGaw Medical Center of Northwestern University