This gets the 'Oh dear God' reaction.
Testicular Tuberculosis | NEJM nejm.org/doi/full/10.10…

Beginning of a new era in treating serious fungal disease?!

🎺Oral Amphotericin B🎺

Oral Lipid Nanocrystal Amphotericin B for Cryptococcal Meningitis: Phase 2 RCT

David Boulware, MD MPH &co.

academic.oup.com/cid/advance-ar…

#IDTwitter
Cheat sheet for intrinsic mech of resistance 📑

What’s your favorite step of #AMRrounds ?
Mine was always Step 4!
Understand acquired resistance mech & interpretive antibiogram
Snacks, PharmD, MPH Jonathan Ryder, MD Timothy Li ID:IOTS podcasting Jenny Dela-Pena Clifton

doi.org/10.1093/jacamr…

one of the best things about the combo of Alex Zimmet & Aruna Subramanian is that they can get absolutely destroyed with new consults on a Sunday and they both remain pleasant and composed ~

like wingless birds, they're #unflappable  🐦

uni transplant centers: hire this man!

my new album, dropping in Oct 2023

1/N Our NEJM Perspective, where Dr. Gregg Gonsalves and I argue for improved surveillance for infectious diseases in US migrant detention centers.

nejm.org/doi/full/10.10…

hi consulting for esbl e. coli uti

sure! oh but i just spoke to patient she has no symptoms

so what would you recommend?

not treating

so how long for the erta?

no erta please

ok we will treat for seven days

i beg you please don’t

can you place an OPAT note?

😩

you know you're ex med/peds when you're in adult HIV clinic and your attending routinely asks (incredulously) 'you want to give them THREE vaccines today?'

oh actually i wanted to do five today

Dr. Edith Lincoln, a pediatrician at the nation’s oldest public hospital, was the first to discover LTBI therapy & her keen observations in the 1950s initiated a cascade of research into rx.

a testament to the intellectual influence of:
- women
- pediatricians
- NYC Health + Hospitals/Bellevue

if we have no test of cure for LTBI, how did we demonstrate that established regimens are *effective*?

why did researchers choose 3 months for 'short' courses? isn't it possible that shorter (eg, 6 weeks) could be as effective?

Jorge Luis Salinas Jason Andrews Aruna Subramanian

Interested in a post-doc/scientist role Stanford University in infectious diseases, epidemiology, modeling, and public health? Come join us!

Multiple post-doc openings (ID modeling, bioinformatics): iddjobs.org/jobs/two-postd…

Lab scientist opening: careersearch.stanford.edu/jobs/lsrp2-226…

an M2 i know is considering doing an MPH while in med school—any advice for her? benefits seem self-evident, but any less conspicuous challenges you'd consider?

feedback from current and former med students is welcome!

themes:
- patient-centered > judgmental/stigmatizing language (patient-directed dc > AMA, adherent > compliant, pts are not “poor historians”, declined > refused)
- therapies fail pts, not vice-versa
- avoid imprecise terms (eg, “dirty” UA)
- update old terms (eg, ART > HAART)

what medical language/phrase/term are you passionate about *not using* that people use all the time? say why you avoid it and suggest an alternative!

i'll go first: 'TB rule-out,' because we can only evaluate for it, we can never rule it out!

alternative: 'pulmonary TB eval'

the risk of developing TB dz is highest in the first 2 years s/p infection, ↓ing thereafter to a lifetime risk of ~10% (ie, ~90% remain w/o dz).

↑ risk for progression to dz:
- infected w/in last 1-2 yrs
- children (<4)
- HIV
- immunocomp'd

TB infxn rx ↓ progression by ~90%.