Very happy to see our long-term project on the functional characterization of an RFX6 mutation enriched in Finns published in Diabetologia. Superb work by Hazem Ibrahim. Read here: rdcu.be/dHX38

Super excited to announce the publication of our research in Diabetologia ! Check out the impact of heterozygous RFX6 mutation in developing diabetes using isogenic SC-islets in vitro and in vivo. Grateful to all the co-authors and the reviewers❤️ link.springer.com/article/10.100…

News from our CoE by OtonkoskiLab Hazem Ibrahim highlights the role of RFX6 in maintaining pancreatic progenitors and uncovers how RFX6 heterozygous loss-of-function affects beta-cell function, increasing the risk for diabetes Suomen Akatemia | Research Council of Finland University of Helsinki link.springer.com/article/10.100…

Hazem’s masterpiece, Congratulations!

How are heterozygous carriers of a RFX6 pathogenic variant predisposed to develop diabetes? Do not miss our latest work, where talented Hazem Ibrahim explored the molecular mechanisms behind monogenic diabetes due to RFX6 mutations:

Less than one month for #EISG24_Helsinki !! Looking forward meeting you all 😃 If you cannot make it to 🇫🇮Helsinki 🇫🇮in person, Virtual Meeting registration is still open until June 17th, do not miss the deadline 🚨 helsinki.fi/en/conferences…

A splice site variant in MADD (a T2D gene) results in reduced beta cell number and increased proinsulin-to-insulin ratio in stem cell derived islets. Beautiful work by Taneli Raivio and colleagues Timo Otonkoski Jonna Saarimäki-Vire , congratulations!

✨ HiLIFE seminar and Jubilee Symposium of Professor Timo Otonkoski 17.6.2024 13.15. ✨ Welcome Andrew Hattersley to give a #hilifewebinars presentation. Registerations by June 6th ➡️ onlinepayments.it.helsinki.fi/product/sympos… 📌 Biomedicum 1, Hall 1, Haartmaninkatu 8 ℹ️ helsinki.fi/en/hilife-hels…

Congrats Diego!!😊

Congrats Väinö! This is a huge study with lots of implications, also for the imaging of focal CHI and islet tumors!

A great start to #EISG2024 in Helsinki with Maike Sander & Lab presenting the latest developments in stem cell islets!

Attending #EISG2024 in Helsinki? Don't miss these must-see spots: Oodi Library, Helsinki Cathedral, Uspenski Cathedral, Suomenlinna Island Sea Fortress, Temppeliaukio Church, Seurasaari Island (especially for Midsummer on 21.6), and the Finnish Museum of Natural History! 🏰🌿📚

Many thanks Heiko, for your kind words and your essential contributions for the success of the meeting !

Thank you to all the attendees and presenters at EISG 2024 in Helsinki! Your contributions made this event a success. Looking forward to seeing you all again in Sweden for EISG2025! 🇫🇮➡️🇸🇪 #EISG2024 #EISG2025

A truly memorable event, thanks to the organizers and everyone involved in ensuring its success!

Huge thanks to all participants EISG 2024! It was great to host you all in Helsinki for three days of exciting islet biology, we had a blast! Big kudos to the organizing team Timo Otonkoski Väinö Lithovius Jonna Saarimäki-Vire Sachin Muralidharan Hazem Ibrahim Tom Barsby Lindahl Maria Kaisa S

Uusi kuvantamismenetelmä diabeteksen soluhoitojen tehon ja turvallisuuden tutkimiseen. Menetelmän avulla voidaan määrittää siirteiden kokoa ja laatua, mikä parantaa diabeteksen solukorvaushoitojen turvallisuutta ja tehokkuutta. Medicine and Health, University of Helsinki Turun yliopisto - University of Turku helsinki.fi/fi/uutiset/ela…

Suomessa muuta maailmaa yleisempi geenimuunnos heikentää insuliinin eritystä ja lisää riskiä sairastua kakkostyypin diabetekseen sekä raskausdiabetekseen. University of Helsinki Hazem Ibrahim OtonkoskiLab helsinki.fi/fi/uutiset/dia…

Very happy to have been able to help in this important study, Congratulations Rocio Sartori Maldonado (she/her) 👩‍🔬 Kirmo and all involved!