Pippa Cosper MD, PhD
@pipcosper
Scientist, Radiation Oncologist, pipetting for life (literally and figuratively). WashU RadOnc, Assistant Prof at UW Madison. Chromosomal instability is my jam
14-02-2019 19:34:23
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Oh lord. Out of 755 oncology phase 3 RCT trials, 20% changed their primary endpoint after the study started. This was associated with trial positivity (!!) and 70% of these did not disclose these changes in the manuscript. What are we doing here??? 😵
jamanetwork.com/journals/jaman…